[HTML][HTML] Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
… There is no consensus or suggestion on which terminology should be used: cytokine storm,
MAS, or sHLH? We chose to use the term cytokine storm secondary to COVID-19; however, …

[HTML][HTML] Autoinflammatory diseases and cytokine storms—imbalances of innate and adaptative immunity

A Marcuzzi, E Melloni, G Zauli, A Romani… - International Journal of …, 2021 - mdpi.com
… Moreover, hyperinflammation is of great interest, as it is one of the main manifestations of
COVID-19 infection, and the cytokine storm and its most important components are the targets …

Constitutive inflammatory cytokine storm: a major threat to human health

KK Gupta, MA Khan, SK Singh - Journal of Interferon & Cytokine …, 2020 - liebertpub.com
… Under inflammatory cytokine storm, the dark gray circles refer to proinflammatory cytokines
and … This review will focus on the inflammatory cytokine storm and its implications on human …

Targeting the “cytokine storm” for therapeutic benefit

RV D'Elia, K Harrison, PC Oyston… - Clinical and Vaccine …, 2013 - Am Soc Microbiol
… tularensis, do trigger life-threatening “cytokine storms” in the host which can result in …
We review some of the current candidates for treatment of cytokine storms which may prove …

[HTML][HTML] Cytokine storm and histopathological findings in 60 cases of COVID-19-related death: from viral load research to immunohistochemical quantification of major …

P Frisoni, M Neri, S D'Errico, L Alfieri… - … Science, Medicine and …, 2022 - Springer
… Current evidence suggests that a cytokine storm is the major cause of acute respiratory
distress syndrome (ARDS) and multiple organ failure and is consistently linked with fatal …

Cytokine storm in the pathophysiology of COVID-19: Possible functional disturbances of miRNAs

M Aslani, SS Mortazavi-Jahromi, A Mirshafiey - International …, 2021 - Elsevier
… This virus induces an intense cytokine response called cytokine storm in a group of patients
with severe/critical form. This event, in turn, results in serious clinical outcomes such as …

Cytokine storm in COVID-19: An overview, mechanism, treatment strategies, and stem cell therapy perspective

NU Azmi, MU Puteri, D Lukmanto - … Sciences and Research, 2020 - scholarhub.ui.ac.id
… Thus, the management of the cytokine storm could be the key to stop COVID-19 progression…
COVID-19, mechanism and prospective treatment strategies for cytokine storm in COVID-19, …

[HTML][HTML] The mechanism behind influenza virus cytokine storm

Y Gu, X Zuo, S Zhang, Z Ouyang, S Jiang, F Wang… - Viruses, 2021 - mdpi.com
… IFNAR is widely present in immune cells, so the IFN-α/β reaction may lead to immunopathology
during the cytokine storm [61]. The tumor necrosis factor (TNF)-related apoptosis-…

[HTML][HTML] Immunopathology of SARS-CoV-2 infection: immune cells and mediators, prognostic factors, and immune-therapeutic implications

A Allegra, M Di Gioacchino, A Tonacci… - International journal of …, 2020 - mdpi.com
… during a cytokine storm by inhibiting specific cytokine signaling such as … , cytokine storm
has a critical role in the process of disease worsening. Therefore, controlling the cytokine storm

The understanding of the immunopathology in COVID-19 infection

D Tascioglu, E Akkaya, S Genc - Scandinavian journal of clinical …, 2021 - Taylor & Francis
… in patients with severe COVID-19 may cause the suppression of CD4 + and CD8 + T cells
and regulatory T cells, causing excessive inflammatory responses and fatal cytokine storm