Immunotherapy summary for cytokine storm in COVID-19

Y Li, W Zhao, J Liu, Z Chen, Q Lv… - Frontiers in Pharmacology, 2021 - frontiersin.org
… not yet sufficient to alleviate the cytokine storm (CS) and systemic inflammatory response
syndrome. How to neutralize the cytokine storm and inhibit excessive immune cell activation …

[HTML][HTML] Immunopathology and immunosenescence, the immunological key words of severe COVID-19. Is there a role for stem cell transplantation?

ME Ligotti, F Pojero, G Accardi, A Aiello… - Frontiers in Cell and …, 2021 - frontiersin.org
… However, which immunopathogenic status precedes this “cytokine storm” and why the male
older population is more severely affected, are currently unanswered questions. The aging …

Molecular mechanisms and signaling pathways involved in immunopathological events of COVID-19

AA Peyvandi, S Niknazar, F Zare Mehrjerdi… - Physiology and …, 2021 - ppj.phypha.ir
Cytokine storms are the main reason of COVID-19-related serious illness and death. The
most significant cause of cytokine storms can be the antibody-dependent enhancement. mTOR …

Targeting purinergic receptors to suppress the cytokine storm induced by SARS-CoV-2 infection in pulmonary tissue

JLB Simões, HF Basso, GC Kosvoski, J Gavioli… - International …, 2021 - Elsevier
… trigger the so-called “cytokine storm”. This process generates … of COVID-19 is a cytokine
storm, one of which is responsible for … The cytokine storm mechanism during a viral infection is …

Comparing the cytokine storms of COVID-19 and pandemic influenza

LM Pacheco-Hernández… - … interferon & cytokine …, 2022 - liebertpub.com
immunopathological aspects of COVID-19 and pandemic influenza from the perspective of
cytokine storms as … Thereby, we analyze similarities and differences in the cytokine profiles of …

[HTML][HTML] Cytokine Storm syndrome in COVID-19 patients: Characteristics And diagnosis

RM Harfouch - Journal of Clinical Epidemiology & …, 2021 - onlinescientificresearch.com
Mechanisms of CSS in COVID-19 The cytokine storm in COVID-19 may have some
differences from the cytokine storms in other clinical settings. Remarkably, the autopsy findings …

Cytokine drizzle—the rationale for abandoning “cytokine storm

AE Stolarski, J Kim, Q Zhang, DG Remick - Shock, 2021 - journals.lww.com
… We propose eliminating the term “cytokine storm” as there is no clear threshold of cytokine
release to define the term nor would an arbitrary threshold imply clinical relevance. There are …

COVID‐19: immunopathology, pathophysiological mechanisms, and treatment options

LE van Eijk, M Binkhorst, AR Bourgonje… - The Journal of …, 2021 - Wiley Online Library
… A bulk of cytokines is induced upon SARS-CoV-2 infection, most of which contribute to
hyperinflammation as constituents of the ‘cytokine storm’ in severe disease (eg IL-6, TNF-α, IL-1β, …

Immunomodulatory agents for COVID-19 treatment: possible mechanism of action and immunopathology features

F Rommasi, MJ Nasiri, M Mirsaeidi - Molecular and cellular biochemistry, 2022 - Springer
… ' possible mechanisms of action. These drugs' mechanism of action generally includes
suppressing or modulating the immune system, preventing the development of cytokine storm via …

[HTML][HTML] Radiotherapy and cytokine storm: risk and mechanism

C Zhang, Z Liang, S Ma, X Liu - Frontiers in Oncology, 2021 - frontiersin.org
… responses induced by radiation, especially the cytokine storm and the underlying mechanisms
such as DAMPs release, pro-inflammatory cytokine secretion and cGAS-STING pathway …