Structure-based drug designing and immunoinformatics approach for SARS-CoV-2

PK Panda, MN Arul, P Patel, SK Verma, W Luo… - Science …, 2020 - science.org
… The discovery of epitope is a key first step in antigen-targeted immunotherapy against viral
… decade, particularly in the light of antiviral immunotherapy (27). The current strategy mainly …

[HTML][HTML] Potential molecular mechanisms of rare anti-tumor immune response by SARS-CoV-2 in isolated cases of lymphomas

D Barh, S Tiwari, L Gabriel Rodrigues Gomes… - Viruses, 2021 - mdpi.com
… -2 protein may interact with the LMP-1 of EBV upon internalization of SARS-CoV-2 into the
cell to … of SARS-CoV-2 may bind to PD-1, similar to the targeted mAb drugs pembrolizumab or …

Immunotherapy in COVID-19: why, who, and when?

P Sinha, CS Calfee - The Lancet Respiratory Medicine, 2021 - thelancet.com
SARS-CoV-2 in health care, most prominently in vaccine development. However, why some
people infected with SARS-CoV-… the host immune response to SARS-CoV-2. Unsurprisingly, …

[HTML][HTML] Special focus 'SARS-CoV-2/COVID-19: advances in developing vaccines and immunotherapeutics'

K Dhama, Y Singh Malik, AA Rabaan… - Human Vaccines & …, 2020 - Taylor & Francis
… , Commentaries) covering various developments, trends, and advances in discovering
effective vaccines and immunotherapies for SARS-CoV-2/COVID-19 along with presenting the …

[HTML][HTML] Host-directed immunotherapy of viral and bacterial infections: past, present and future

RS Wallis, A O'Garra, A Sher, A Wack - Nature Reviews Immunology, 2023 - nature.com
… Indicated are the time of discovery or first description for corticosteroids, interferons, IL-2,
IL-… with their successful uses in humans as immunotherapies for the indicated non-infectious …

[HTML][HTML] Overview of immune response during SARS-CoV-2 infection: lessons from the past

VK Shah, P Firmal, A Alam, D Ganguly… - Frontiers in …, 2020 - frontiersin.org
… Later, it was discovered that an essential proteolytic cleavage event takes … SARS-CoV-2
to some extent (85). These epitopes could be a promising factor in developing immunotherapy

An immunotherapeutic method for COVID-19 patients: a soluble ACE2-Anti-CD16 VHH to block SARS-CoV-2 Spike protein

A Sheikhi, M Hojjat-Farsangi - Human Vaccines & …, 2021 - Taylor & Francis
… Coronaviruses, including the newly discovered SARS-CoV-2, are spherical single-stranded
RNA viruses, characterized by spike proteins, projecting from the virion surface. The …

[HTML][HTML] Neurological immunotherapy in the era of COVID-19—looking for consensus in the literature

C Korsukewitz, SW Reddel, A Bar-Or… - Nature reviews …, 2020 - nature.com
… are receiving immunotherapy. Uncertainty remains about whether immunotherapies increase
the risk of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or …

[HTML][HTML] Structural biology of SARS-CoV-2: open the door for novel therapies

W Yan, Y Zheng, X Zeng, B He, W Cheng - Signal Transduction and …, 2022 - nature.com
… The discovery of therapy reagents for treating COVID-19 are urgently needed, and the …
g–i footprint of a representative antibody from the Coronavirus Immunotherapeutic Consortium (…

Treatment and prevention strategies for the COVID 19 pandemic: a review of immunotherapeutic approaches for neutralizing SARS-CoV-2

PK Baral, J Yin, MNG James - International journal of biological …, 2021 - Elsevier
discovered to play a role in the development of the ACE2-… targeting various epitopes on the
SARS CoV-2 spike protein … conserved regions within the SARS CoV and SARS CoV-2 spike …