SARS-CoV-2–specific T cells are rapidly expanded for therapeutic use and target conserved regions of the membrane protein

MD Keller, KM Harris… - Blood, The Journal …, 2020 - ashpublications.org
… that SARS-CoV-2 directed T-cell immunotherapy targeting … for the prevention or early
treatment of SARS-CoV-2 infection in … , including the novel discovery that SARS-CoV-2–specific T …

Inflammation, immunity and potential target therapy of SARS-COV-2: A total scale analysis review

SW Smail, M Saeed, ZO Khudhur, DA Younus… - Food and Chemical …, 2021 - Elsevier
Immunotherapeutic strategies Here, we focus on promising immunotherapies that increase
immunity against SARS-CoV-… The application of immunotherapeutic drugs that mostly act as …

Anti-SARS-CoV-2 and anti-cytokine storm neutralizing antibody therapies against COVID-19: Update, challenges, and perspectives

CM Batista, L Foti - International Immunopharmacology, 2021 - Elsevier
… ABT passive immunotherapy is based on nAbs to keep pathogens from entering the host
cell… the fastest discovery of ABT for SARS-CoV and SARS-CoV-2 in science history [43]. …

Discovery of Antibody-Based Immunotherapy and Applications for Emerging Infectious Diseases

M Ejemel - 2022 - search.proquest.com
… Extensive sequence analysis of the antibody epitope to SARS CoV-2 Wuhan variant
revealed a conserved epitope in all SARS CoV-2 variants including Beta, Gamma, and most …

A novel hypothesis for original antigenic sin in the severe disease of SARS-CoV-2 infection

H Kohler, P Nara - … in Immunodiagnosis and Immunotherapy, 2020 - liebertpub.com
In this hypothesis, we address the biological/immunological pathway leading to severe
disease or death after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV

Mass spectrometric identification of immunogenic SARS-CoV-2 epitopes and cognate TCRs

K Pan, Y Chiu, E Huang, M Chen… - Proceedings of the …, 2021 - National Acad Sciences
… to recognize and kill SARS-CoV-2 target cells. We report here several SARS-CoV-2 epitopes
… The antigen discovery platform for SARS-CoV-2 comprises four steps: 1) peptide elution …

Vaccines and therapies in development for SARS-CoV-2 infections

D Wu, R Koganti, UP Lambe, T Yadavalli… - Journal of clinical …, 2020 - mdpi.com
… The amino acid mutations in the RBD from SARS-classic to SARS-CoV-2 include the … in
SARS-CoV-2 than SARS-CoV [22]. Moreover, several residue changes in the SARS-CoV-2 RBD …

Immunopathology of SARS-CoV-2 infection: immune cells and mediators, prognostic factors, and immune-therapeutic implications

A Allegra, M Di Gioacchino, A Tonacci… - International journal of …, 2020 - mdpi.com
… cellular and humoral immune changes induced by SARS-CoV-2 and to propose the possibility
… the immunotherapeutic approach is of fundamental importance for SARS-CoV-2 infection. …

Anti-SARS coronavirus agents: a patent review (2008–present)

V Kumar, YS Jung, PH Liang - Expert opinion on therapeutic …, 2013 - Taylor & Francis
… Since the discovery of the causative agent of SARS, the SARS-CoV, sequencing of its …
Among the efforts, developing immunotherapy such as neutralizing monoclonal antibodies and …

[PDF][PDF] Approaches to Immunotherapy, Drugs for Treatment of COVID-19, Mechanism of Action and Challenges

S Irfan - Saudi J Med, 2021 - saudijournals.com
SARS CoV, Middle East respiratory syndrome related coronavirus (MERS CoV), and other
coronavirus vaccines revealed several safety concerns associated with the use of coronavirus