[HTML][HTML] Merits and culprits of immunotherapies for neurological diseases in times of COVID-19

M Pawlitzki, UK Zettl, T Ruck, L Rolfes, HP Hartung… - …, 2020 - thelancet.com
… on the extent to which immunotherapies must be continued, … the novel coronavirus and the
approved immunotherapies for … but also the potential of immunotherapies to treat COVID-19. …

Current status of therapeutic monoclonal antibodies against SARS-CoV-2

S Kumar, A Chandele, A Sharma - PLoS pathogens, 2021 - journals.plos.org
… ) against SARS-CoV-2 was approved for passive immunotherapy … against SARS-CoV-2 and
its rapidly emerging variants. … mAbs production since the discovery of mAbs [12]. Currently, 8 …

Functional characterization of CD4+ T cell receptors crossreactive for SARS-CoV-2 and endemic coronaviruses

AG Dykema, B Zhang, BA Woldemeskel… - The Journal of …, 2021 - Am Soc Clin Investig
… acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in … ligand, has never been shown
in the context of SARS-CoV-2. … the spike (S) glycoproteins of SARS-CoV-2 and CCCs at the …

Structure-based development of human antibody cocktails against SARS-CoV-2

N Wang, Y Sun, R Feng, Y Wang, Y Guo, L Zhang… - Cell research, 2021 - nature.com
… (NAb) responses to SARS-CoV-2 could facilitate vaccine design and drug discovery. Spike
(S) … , when selective pressure is applied in immunotherapies, resulting in resistance against …

[HTML][HTML] Interleukin-6 in SARS-CoV-2 induced disease: Interactions and therapeutic applications

J Majidpoor, K Mortezaee - Biomedicine & Pharmacotherapy, 2022 - Elsevier
… targeting this cytokine in patients with SARS CoV-2 induced disease. We also have a
discussion over IL-6 roles in patients with SARS CoV-2 induced disease who also have cancer. …

COVID-19 severity and mortality in multiple sclerosis are not associated with immunotherapy: Insights from a nation-wide Austrian registry

G Bsteh, H Assar, H Hegen, B Heschl, F Leutmezer… - PLoS …, 2021 - journals.plos.org
Background The COVID-19 pandemic challenges neurologists in counselling patients with
multiple sclerosis (pwMS) regarding their risk by SARS-CoV-2 and in guiding disease-…

FcγRIIb blockage: a promising immunotherapy target for severe COVID-19

X He, M Wang, M Wu - Signal Transduction and Targeted Therapy, 2021 - nature.com
… This important discovery represents a major insight into the separate, distinct mechanism in
… in severe disease cases could not protect against SARS-CoV-2 infection, rather aggravating …

An overview of pivotal trials and real-world evidence for CD20-depleting therapy in multiple sclerosis: Immunotherapy with rituximab, ocrelizumab, and ofatumumab

A Ovchinnikov, O Findling - Wiener Medizinische Wochenschrift, 2022 - Springer
… of SARS-CoV‑2 [23]. Recent data further demonstrated that these patients had a reduced
humoral immune response after standard SARS-CoV… vaccination against SARS-CoV‑2 [26, 27]. …

T and B cell Epitope analysis of SARSCoV‐2 S protein based on immunoinformatics and experimental research

Z Chen, P Ruan, L Wang, X Nie, X Ma… - Journal of cellular and …, 2021 - Wiley Online Library
… ‐2, which might play roles in the initiation of SARSCoV‐2 … T cell response similar to that of
SARSCoV‐2 infection. Moreover, the … new vaccine targets to prevent SARSCoV‐2 infection. …

[HTML][HTML] Drug development strategies and immunological aspects of SARS-CoV-2

S Maitra, N Mukerjee, A Dey… - The Open Public …, 2022 - openpublichealthjournal.com
… The discovery of a novel infectious agent from the Coronaviridae family was made possible
SARS-CoV-2 is a member of the coronavirus family, a large and diverse group of viruses …