… individuals in the early phase in life, determine precision medicine methods based on their
… impact of human genetics for CVD and how to translate this information into our daily clinical …

… J Inter Med 2003; 253: 120–127. Coronary heart disease (CHD) is one of the main leading
causes of death worldwide. CHD is a complex condition resulting from numerous gene–gene …

Our understanding of the genetic basis of cardiovascular diseases (CVDs) has evolved
rapidly. This has resulted from a combination of dedicated research in well phenotyped CVD …

… , complex forms of cardiovascular disease. We also discuss key … insights, with an emphasis
on the impact of next-generation … sequencing and modeling human genetic disease in cells. …

… alike, cardiovascular genetics is having a growing impact on the definition and diagnosis of
… of the human genetic disease familial hypercholesterolemia (FH); they postulated that the …

… risk of coronary heart disease (CHD) mortality in men but not in women. Increased relative
risk for all-cause mortality was present in both men and women in this study population. …

… studies in cardiovascular conditions, we performed a qualitative study to explore the impact
of … This was part of a medical–ethical evaluation of predictive testing of minors for hereditary …

… testing, has the potential to impact the practice of cardiovascular medicine and research. …
We recommend a large investment in an infrastructure to catalog human genetic variation. Such …

… undergone clinical genetic testing or who underwent clinical genetic testing after receiving
… to the heterogeneous genetic etiology of inherited cardiovascular diseases. Because there …

… CHD risk factors and most of the "classic" CHD risk factors show … with several cardiovascular
risk factors and well-defined genetic … of coronary artery disease in the young adult: Effects of …