[HTML][HTML] Increased resistance of SARS-CoV-2 variant P. 1 to antibody neutralization

P Wang, RG Casner, MS Nair, M Wang, J Yu… - Cell host & …, 2021 - cell.com
… to multiple neutralizing monoclonal antibodies but also more resistant to neutralization by …
The magnitude of resistance is greater for monoclonal antibodies than vaccinee sera and …

Antibody neutralization and escape by HIV-1

X Wei, JM Decker, S Wang, H Hui, JC Kappes, X Wu… - Nature, 2003 - nature.com
… In the first 391 days of infection, increasing Nab activity was … -55) which was resistant to
neutralization by day 136 plasma … led to a 20-fold increase in neutralization sensitivity, but the …

[HTML][HTML] Increased resistance of SARS-CoV-2 Lambda variant to antibody neutralization

H Guo, Q Fan, S Song, S Shen, B Zhou, H Wang… - Journal of Clinical …, 2022 - Elsevier
… In addition, the neutralization test with 12 published … neutralization by some antibodies
from Class 2 and Class 3. Overall, these results suggest that pre-existing antibody neutralization

[HTML][HTML] Increased resistance of SARS-CoV-2 variants B. 1.351 and B. 1.1. 7 to antibody neutralization

D Ho, P Wang, L Liu, S Iketani, Y Luo, Y Guo, M Wang… - 2021 - europepmc.org
… the neutralizing activity of six NTD mAbs against UKΔ8, SAΔ9, and WT pseudoviruses. Both
UKΔ8 and SAΔ9 are profoundly resistant to neutralization by our antibodies … the resistance of …

Increased resistance of SARS-CoV-2 Omicron variant to neutralization by vaccine-elicited and therapeutic antibodies

T Tada, H Zhou, BM Dcosta, MI Samanovic… - …, 2022 - thelancet.com
increased neutralizing titres against Omicron. Neutralizing titres against Omicron were increased
… Analysis of the therapeutic monoclonal antibodies showed that the Regeneron and Eli …

Neutralizing antibody therapeutics for COVID-19

AC Hurt, AK Wheatley - Viruses, 2021 - mdpi.com
… of SARS-CoV-2 neutralizing antibodies (nAbs) in the clinical … of treatment-emergent antiviral
resistant “escape” mutants … identified that increase affinity to FcRn to extend antibody half-life …

The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic

M Hoffmann, N Krüger, S Schulz, A Cossmann… - Cell, 2022 - cell.com
… spike was resistant against most therapeutic antibodies but … Similarly, the Omicron spike
evaded neutralization by antibodies … reduce antibody binding or increase spike expression ( …

Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies

RE Chen, X Zhang, JB Case, ES Winkler, Y Liu… - Nature medicine, 2021 - nature.com
… 3l) viruses, we detected no change or small significant increases (1.5-fold, P < 0.05) in
neutralization, respectively. The heat map analysis showed that all NHP sera consistently …

A diverse panel of hepatitis C virus glycoproteins for use in vaccine research reveals extremes of monoclonal antibody neutralization resistance

RA Urbanowicz, CP McClure, RJP Brown… - Journal of …, 2016 - Am Soc Microbiol
… Finally, resistance to MAb neutralization was correlated with the degree of infectivity, as …
Such a relationship between increased antibody neutralization resistance and improved HCVpp …

Evasion of antibody neutralization in emerging severe acute respiratory syndrome coronaviruses

Z Yang, HC Werner, W Kong, K Leung… - Proceedings of the …, 2005 - National Acad Sciences
… We find that some S variants were resistant to neutralization, whereas others, … increased
affinity of SARS-CoV S for this receptor (5), and it therefore appears the Ab neutralization and …