D Ho, P Wang, L Liu, S Iketani, Y Luo, Y Guo, M Wang… - 2021 - europepmc.org
… Our findings have relevance to the use of mAb to treat or prevent SARS-CoV-2. Both UKΔ8 and SAΔ9 are resistant to neutralization by mAbs directed to the NTD supersite (Figs. 2c, 2d, …
T Tada, H Zhou, BM Dcosta, MI Samanovic… - …, 2022 - thelancet.com
… -34-fold resistance to Pfizer BNT162b2 and … increased neutralizing titres against Omicron. Neutralizing titres against Omicron were increased in the sera with a history of prior SARS-CoV…
… Because antibody-based interventions for SARS-CoV-2 face increasingresistance from the emergence of variants of concern, antivirals with alternative modes of action have increased …
… The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants … virulence, re-infection frequency, and increasedresistance to the action of monoclonal and …
FV Segala, DF Bavaro, F Di Gennaro, F Salvati… - Viruses, 2021 - mdpi.com
… led to an increased incidence of MDRGNs colonization and infections [41]. A particular concern was caused by the increasing incidence of carbapenem-resistant Enterobacteriaceae (…
… The ongoing SARS-CoV-2 pandemic has highlighted the … for the emergence of antibiotic resistances due to the increased use of … QACs are extensively used in SARS-CoV-2-related …
K Guo, BS Barrett, JH Morrison… - Proceedings of the …, 2022 - National Acad Sciences
… transmissibility, pathogenesis, and resistance to neutralizing antibodies have emerged. … variants of SARS-CoV-2. Our data revealed increased interferon resistance in SARS-CoV-2 …
… acid changes in the S protein of the SARS-CoV-2 genomes deposited in the GISAID database … This analysis showed that the effective population size of the Lambda variant increased at …
Y Duan, H Zhou, X Liu, S Iketani, M Lin, X Zhang… - Nature, 2023 - nature.com
… The molecular mechanisms for this observed resistance are … can allow SARS-CoV-2 to develop resistance to nirmatrelvir in … S4′ subsites unexpectedly increased protease activity. Both …