[HTML][HTML] Increased resistance of SARS-CoV-2 variant P. 1 to antibody neutralization

P Wang, RG Casner, MS Nair, M Wang, J Yu… - Cell host & …, 2021 - cell.com
The emergence of SARS-CoV-2 variants has raised concerns about altered sensitivity to
antibody-mediated immunity. The relative resistance of SARS-CoV-2 variants B.1.1.7 and B.…

[HTML][HTML] Increased resistance of SARS-CoV-2 variants B. 1.351 and B. 1.1. 7 to antibody neutralization

D Ho, P Wang, L Liu, S Iketani, Y Luo, Y Guo, M Wang… - 2021 - europepmc.org
… Our findings have relevance to the use of mAb to treat or prevent SARS-CoV-2. Both UKΔ8
and SAΔ9 are resistant to neutralization by mAbs directed to the NTD supersite (Figs. 2c, 2d, …

Increased resistance of SARS-CoV-2 Omicron variant to neutralization by vaccine-elicited and therapeutic antibodies

T Tada, H Zhou, BM Dcosta, MI Samanovic… - …, 2022 - thelancet.com
… -34-fold resistance to Pfizer BNT162b2 and … increased neutralizing titres against Omicron.
Neutralizing titres against Omicron were increased in the sera with a history of prior SARS-CoV

Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir

S Iketani, H Mohri, B Culbertson, SJ Hong, Y Duan… - Nature, 2023 - nature.com
… Because antibody-based interventions for SARS-CoV-2 face increasing resistance from the
emergence of variants of concern, antivirals with alternative modes of action have increased

Emerging SARS-CoV-2 variants and impact in global vaccination programs against SARS-CoV-2/COVID-19

CE Gómez, B Perdiguero, M Esteban - Vaccines, 2021 - mdpi.com
… The emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants
… virulence, re-infection frequency, and increased resistance to the action of monoclonal and …

Impact of SARS-CoV-2 epidemic on antimicrobial resistance: a literature review

FV Segala, DF Bavaro, F Di Gennaro, F Salvati… - Viruses, 2021 - mdpi.com
… led to an increased incidence of MDRGNs colonization and infections [41]. A particular
concern was caused by the increasing incidence of carbapenem-resistant Enterobacteriaceae (…

The silent pandemic: Emergent antibiotic resistances following the global response to SARS-CoV-2

AR Mahoney, MM Safaee, WM Wuest, AL Furst - Iscience, 2021 - cell.com
… The ongoing SARS-CoV-2 pandemic has highlighted the … for the emergence of
antibiotic resistances due to the increased use of … QACs are extensively used in SARS-CoV-2-related …

Interferon resistance of emerging SARS-CoV-2 variants

K Guo, BS Barrett, JH Morrison… - Proceedings of the …, 2022 - National Acad Sciences
… transmissibility, pathogenesis, and resistance to neutralizing antibodies have emerged. …
variants of SARS-CoV-2. Our data revealed increased interferon resistance in SARS-CoV-2 …

The SARS-CoV-2 Lambda variant exhibits enhanced infectivity and immune resistance

I Kimura, Y Kosugi, J Wu, J Zahradnik, D Yamasoba… - Cell reports, 2022 - cell.com
… acid changes in the S protein of the SARS-CoV-2 genomes deposited in the GISAID database
… This analysis showed that the effective population size of the Lambda variant increased at …

Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir

Y Duan, H Zhou, X Liu, S Iketani, M Lin, X Zhang… - Nature, 2023 - nature.com
… The molecular mechanisms for this observed resistance are … can allow SARS-CoV-2 to
develop resistance to nirmatrelvir in … S4′ subsites unexpectedly increased protease activity. Both …