… This study was undertaken to assess the pharmacokinetics and developmental toxicity of
the anticonvulsant, valproic acid (VPA), a human teratogen, in Sprague-Dawley rats. Oral …

… of rats prenatally exposed to valproic acid (VPA), a well-characterized experimental
model of autism. Pregnant rats … Control rats were injected with saline. On the fourteen-postnatal-day, …

… USV emissions in isolated male and female infant rats. … of ASD is prenatal exposure to
valproic acid (VPA). Despite high … Typically, pregnant rats are injected with a single dose of VPA …

… A multi‐age rat model was evaluated as a means to identify a potential age‐… valproic acid
(VPA), a known pediatric hepatotoxic agent. Different age groups of Sprague‐Dawley (SD) rats …

… from control and VPA-exposed rats at different ages. We observed an enhancement of both
group I and group II mGlu receptor expressions in infant rats prenatally exposed to VPA and …

… Studies have shown that the infant rat can emit the highest number of ultrasounds on the
7th day after birth (PND7). The number is often used as an indicator to check whether the early …

… The study included nine infants born to mothers who used valproic acid mono- … cohort of 14
infants born to women using valproic acid monotherapy. It was not clear whether any of these …

… in vivo exposure of rat embryos to valproic acid during the … Unpublished data also indicate
that the brain stems of these rats … of valproate-exposed rats; these results are reported herein. …

… infant rat with ASD induced by VPA significantly improved development and behavior of
rats … In this study, we used valproic acid (VPA)-induced rat model of ASD to study the role of …

… -dependent methyl biosynthesis in the rat. Neurochem Res 11:… response of rat conceptuses
exposed to valproic acid (VPA) in … in infants born to women receiving valproic acid. J Pediatr …