… endogenous mouse … mice are highly susceptible to SARS-CoV-2 infection via
intranasal inoculation, and the viral kinetics and pathological outcomes seen in the SARS-CoV-2-infected …

… -coronavirus (SARS-CoV) infection in C57BL/6 mice. A clinical isolate of the virus introduced
intranasally replicated transiently to high levels in the lungs of these mice, … 2, the SARS-CoV …

… human infections. One limitation to the evaluation of potential therapies and vaccines to
inhibit SARS-CoV-2 infection … laboratory strains of mice are not readily infected by SARS-CoV-2 …

… tools is available for mice. The use of mice to study SARS-CoV-2 infection provides the
potential for a broader understanding of several different aspects of this complex disease. …

… Similarities between murine infection with MHV and human infection with SARS CoV-2
include their affinity for the olfactory system (MHV-A59) and pulmonary system (MHV-1), their …

… Using whole-body plethysmography, we found that young adult mice infected with SARS-CoV-2
MA showed a small but significant change in PenH (Fig. 2d) and a significant decrease …

… course of SARS-CoV-2 infection in K18-hACE2 transgenic mice. … mice, which observed
successful infection with SARS-CoV-2 and a milder disease severity compared with SARS-CoV-1…

… This indicated the high susceptibility of hACE2 transgenic mouse model intranasal infection
of SARS-CoV-2 and this model resembled the mild cases of COVID-19, but not the severe …

… relationship between neuroinvasion and ischemic infarcts, we pose a possible hypothesis
from our findings in the patients, mice, and infections of human brain organoids: that SARS-…

… with one of the earliest known isolates of SARS-CoV-2, our mouse model of SARS-CoV-2
infection exhibits viral replication in the lungs characterized by moderate interstitial pneumonia…