… inflammasome activation. In this review, we summarize recent advances in NLRP3 inflammasome
activation and inhibitors that … for treating NLRP3 inflammasome-mediated diseases. …

… Hence, a suite of tool compounds and natural compounds have been reported to inhibit
inflammasome activation in recent years, and some molecules are currently being evaluated in …

… Early studies suggested the role of mtROS in NLRP3 inflammasome activation when they
noted the inhibition of NADPH oxidase-dependent mtROS prevents ATP-induced caspase-1 …

… NLRP3 inflammasome activation leads to release of … Dysregulation of the NLRP3
inflammasome pathway is closely … Emerging studies have suggested NLRP3 inflammasome as a …

… to canonical inflammasome (… inflammasome pathways, NLRP3 inflammasome activation
leads to the maturation and secretion of IL-1β and IL-18. Similar to the chloride efflux inhibitors, …

… inhibitor, we hypothesized that the inhibitory effect of Rux on the activation of the NLRP3
inflammasome … be achieved through the regulation of STAT3 activation. To explore the interplay …

… p202 protein interact with AIM2 to inhibit inflammasome activation. ?, indicates that … pathway.
A number of PYD-containing proteins have been found to inhibit the AIM2 inflammasome. In …

… inhibition of NLRP3 inflammasome activation via modulating extracellular signal-regulated
kinase phosphorylation. Curcumin also suppressed NLRP3 inflammasome activation in …

… Both bromoxone and 5Z-7-oxozeaenol, the two inflammasome pathway inhibitors we … This
promoted us to explore the possibility of identifying more inflammasome pathway inhibitors …

… flavonoids inhibit NLRP3 inflammasome activation pathway in … initially examined for NLRP3
inflammasome activation. It was … are true inhibitors of NLRP3 inflammasome activation. …