… , with the transcription factor NF-κB serving as the major lynchpin… NF-κB in linking inflammation
to cancer. However, rather than providing a detailed summary of the inflammation-cancer …

… In summary, much has been learned about the role of inflammation and inflammatory
processes in the pathogenesis of cancer by studying the oncogenic functions of NF-κB. It is our …

… whereby NF-κB plays key positive roles in linking inflammation … NF-κB in linking inflammation
with tumor development: colitis-… colon cancer (CAC), a classical inflammation-driven cancer …

… In this review, we provide an overview of the most relevant modes of crosstalk and
cooperativity between NF-κB and other signaling molecules during inflammation and cancer. …

… of NF-κB, as well as the basic mechanisms of NF-κB … effects of dysregulated NF-κB on
inflammation, tumorigenesis… targeting NF-κB for inflammatory diseases and cancer treatment and …

It has long been suspected that NF-κB signaling has a pivotal role in chronic inflammation-associated
malignancies, although genetic evidence for this hypothesis has been lacking. …

… In the following sections, we discuss the mechanisms by which these inhibitors alter the
NF-κB pathway in inflammatory states and cancer. Inhibition of the NF-κB pathway using …

… pylori results in a concomitant activation of the NF-κB pathway [19], which results in
expression of one of the NFκB target genes – an inflammatory cytokine IL-8. Several …

… that connect infection, inflammation and cancer, and it puts … -κB (NF-κB) by the classical,
IKK-β (inhibitor-of-NF-κB kinase-β)-dependent pathway is a crucial mediator of inflammation-…

… Although links between cancer and inflammation were firstly proposed in the nineteenth …
infections and inflammation as major risk factors for various types of cancer. NF-κB transcription …