… extracellular signal-regulated kinase (ERK) family, are ubiquitous among eukaryotes. Recent
work has defined two cascades activated preferentially by the inflammatory cytokines TNF-…

… These three cytokines are not only pyrogens that help the body fight infection, … inflammatory
signaling cascades, and that can have pathological consequences. In addition, the cytokine …

… the critical inflammatory cytokines include … signaling cascades, including: 1) the activation
of the JAK (Janus kinase), resulting in the phosphorylation-induced activation of STAT (signal …

… Importantly, the genes encoding the Socs proteins are direct targets of Stat proteins; the
Jak-Stat cascades thereby control their own signaling output by feedback inhibition. Although …

… the induction of inflammatory cytokines and glial proliferation… inflammatory cytokines, and
further analyzed signaling molecules that are relevant to the induction of inflammatory cytokines…

… Inflammatory responses arise as an outcome of tissues or … It is a complex cascade of immune
mechanism to overcome … and amines, pro-inflammatory cytokines, eicosanoids and acute-…

… of TNF- α in the pathogenesis of HF, we review the effects of TNF- α on the physiology of the
heart and the development of clinical strategies to target the inflammatory cytokine cascade. …

… of the signal transducing pathways of inflammatory and anti-inflammatory cytokines and …
or disrupting its downstream signaling cascade leads to inflammatory disease. For example, …

… including the mitogen-activated protein kinase (MAPK) signal transduction pathway, which
… to sites of inflammation. Stimulation of leukocytes by pro-inflammatory cytokines is known to …

… by dendritic cells or inflammatory cytokines, and how these T-… to produce pro-inflammatory
cytokines (tumour necrosis factor α… main initiator of the coagulation cascade in vivo, and finally …