Weathering the cytokine storm in COVID-19: therapeutic implications

G Iannaccone, R Scacciavillani, MG Del Buono… - Cardiorenal …, 2020 - karger.com
… CS are the cornerstone of treatments for cytokine storms and macrophage activation … forms
of CRS to curb the systemic inflammatory response and prevent the occurrence of ARDS, if …

The cytokine storm in COVID-19: Further advances in our understanding the role of specific chemokines involved

F Coperchini, L Chiovato, G Ricci, L Croce… - Cytokine & Growth …, 2021 - Elsevier
… CCL2 is constitutively expressed for homeostatic functions such as regulating lymphocyte
trafficking from blood to lymph nodes, while it is induced during inflammatory responses when …

Cytokine storm may not be the chief culprit for the deterioration of COVID-19

Y Gao, C Wang, K Kang, Y Peng, Y Luo, H Liu… - Viral …, 2021 - liebertpub.com
… infection, but uncontrolled host immune response, which was used to … cytokine storm was
characterized by simultaneous activation of proinflammatory and anti-inflammatory responses (…

[HTML][HTML] Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
… concerns about the enhanced immune response after COVID-19 … and inflammatory response
and to verify if the vaccination program is an effective strategy to prevent the cytokine storm. …

[HTML][HTML] May the central nervous system be fogged by the cytokine storm in COVID-19?: an appraisal

YH Balcioglu, UH Yesilkaya, H Gokcay… - Journal of Neuroimmune …, 2020 - Springer
storm, a well-known phenomenon led by SARS-CoV-2 infection. … to an aggressive inflammatory
response. Thus, the intense release of proinflammatory cytokines (viz cytokine storm) in …

Role of host immune and inflammatory responses in COVID-19 cases with underlying primary immunodeficiency: a review

BM Liu, HR Hill - Journal of Interferon & Cytokine Research, 2020 - liebertpub.com
… COVID-19 is characterized by cytokine storm syndromes due to innate immune activation. …
could also lead to suppressed inflammatory responses and cytokine storm. It remains an open …

[PDF][PDF] Coronavirus-19 (SARS-CoV-2) induces acute severe lung inflammation via IL-1 causing cytokine storm in COVID-19: a promising inhibitory strategy

P Conti, A Caraffa, CE Gallenga, R Ross… - J Biol Regul Homeost …, 2020 - researchgate.net
… pro-inflammatory cytokines that can induce a cytokine storm that can lead to patient death.
IL… the principal function of which is to mediate host inflammatory responses (7). The IL-1 …

[HTML][HTML] Coronavirus disease 2019 (COVID-19): cytokine storms, hyper-inflammatory phenotypes, and acute respiratory distress syndrome

S Lin, Y Zhao, D Zhou, F Zhou, F Xu - Genes & Diseases, 2020 - Elsevier
… host inflammatory responses of ARDS during cytokine storms … and mechanisms of cytokine
storms, host responses, severe … to hyper-inflammatory host responses in ARDS that play a …

An interferon‐γ‐related cytokine storm in SARS patients

KJ Huang, IJ Su, M Theron, YC Wu… - Journal of medical …, 2005 - Wiley Online Library
… Since SARS-CoV infection can be fatal, and intensive inflammatory response is involved in
the disease process, we compared the cytokines between death and survival cases of SARS …

[HTML][HTML] Autoinflammatory diseases and cytokine storms—imbalances of innate and adaptative immunity

A Marcuzzi, E Melloni, G Zauli, A Romani… - International Journal of …, 2021 - mdpi.com
… IL-1β, a primary pro-inflammatory cytokine, which plays a fundamental role both in innate
immunity and inflammatory responses [58,59]. This cytokine is secreted by different cell types, …