[PDF][PDF] Coronavirus-19 (SARS-CoV-2) induces acute severe lung inflammation via IL-1 causing cytokine storm in COVID-19: a promising inhibitory strategy

P Conti, A Caraffa, CE Gallenga, R Ross… - J Biol Regul Homeost …, 2020 - researchgate.net
… pro-inflammatory cytokines that can induce a cytokine storm that can lead to patient death.
IL… the principal function of which is to mediate host inflammatory responses (7). The IL-1 …

[HTML][HTML] Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
… concerns about the enhanced immune response after COVID-19 … and inflammatory response
and to verify if the vaccination program is an effective strategy to prevent the cytokine storm. …

[HTML][HTML] Cytokine storm: the primary determinant for the pathophysiological evolution of COVID-19 deterioration

R Chen, Z Lan, J Ye, L Pang, Y Liu, W Wu… - Frontiers in …, 2021 - frontiersin.org
cytokine storms promote the deterioration of COVID-19. Here, we outline the pathophysiological
processes through which cytokine storms … of immune response dysfunction that leads to …

An interferon‐γ‐related cytokine storm in SARS patients

KJ Huang, IJ Su, M Theron, YC Wu… - Journal of medical …, 2005 - Wiley Online Library
… Since SARS-CoV infection can be fatal, and intensive inflammatory response is involved in
the disease process, we compared the cytokines between death and survival cases of SARS …

[PDF][PDF] Mast cells activated by SARS-CoV-2 release histamine which increases IL-1 levels causing cytokine storm and inflammatory reaction in COVID-19

P Conti, A Caraffa, G Tetè, CE Gallenga… - J Biol Regul Homeost …, 2020 - researchgate.net
… -response of immune cells, including virus-activated macrophages and mast cells (MCs). The
local inflammatory response in … network of activated inflammatory innate immune cells and …

Cytokine storm and sepsis disease pathogenesis

BG Chousterman, FK Swirski, GF Weber - Seminars in immunopathology, 2017 - Springer
… the inflammatory response or targeting the cytokines failed. The … cytokine storm and its
effects. In this review, we will detail the mechanisms leading to the induction of the cytokine storm

Distinct inflammatory profiles distinguish COVID-19 from influenza with limited contributions from cytokine storm

PA Mudd, JC Crawford, JS Turner, A Souquette… - Science …, 2020 - science.org
inflammatory host responses and the respiratory failure observed in patients with COVID-19,
we undertook a comparative investigation of inflammatory responses … immune response in …

[HTML][HTML] Role of inflammatory cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
inflammatory response or cytokine storm. Convalescent plasma therapy, antibody-based
therapies, mesenchymal stem cell therapies, and medicinal herbs have shown potential to …

[HTML][HTML] Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

KE Remy, M Mazer, DA Striker, AH Ellebedy… - JCI insight, 2020 - ncbi.nlm.nih.gov
… -19 (15, 33), could exacerbate a dysfunctional and robust inflammatory response and
worsen organ injury. … To evaluate the inflammatory response over time, we measured plasma …

Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China and emerging pathogenesis and …

J Wang, M Jiang, X Chen… - Journal of Leucocyte …, 2020 - academic.oup.com
… The severe inflammatory responses induced by a cytokine storm start locally and spread
systemically, causing collateral damage in tissues. To date, it is unclear what determinants of …