L D'Ignazio, D Bandarra, S Rocha - The FEBS journal, 2016 - Wiley Online Library
… Although HIF is mainly associated with the hypoxia response, the last few years … for HIF in the inflammationresponse. Numerous studies have shown that HIF-1α is induced in response …
MI Malkov, CT Lee, CT Taylor - Cells, 2021 - mdpi.com
… HIF-dependent signaling at sites of inflammation. We report extensive evidence for these cytokines directly impacting upon HIF signaling through the regulation of HIF … inflammatory and …
L Tacchini, E Gammella, C De Ponti, S Recalcati… - Journal of Biological …, 2008 - ASBMB
… dependent ferroportin down-regulation (eg iron uptake) may be important for iron sequestration within reticuloendothelial cells during the very early phase of the inflammatoryresponse. …
M Tian, W Liu, X Li, P Zhao, MA Shereen… - … and Targeted Therapy, 2021 - nature.com
… in glycolysis and inflammatoryresponse, 12 our data suggests that HIF-1 … inflammatory responses. Notably, 10 genes in the HIF-1α pathway, including the hypoxia-induciblefactor-1α (…
R Feinman, EA Deitch, AC Watkins… - American Journal …, 2010 - journals.physiology.org
… Given that HIF-1 is capable of modulating the innate immune and inflammatoryresponses in hematopoietic and nonhematopoietic cells, we determined whether HIF-1 activation …
… the critical role of HIF-1α in infiltration at the very earliest stages of inflammatory cell recruitment. We present evidence that HIF-1α controls inflammatoryresponse through its regulation …
JE Albina, B Mastrofrancesco… - … of Physiology-Cell …, 2001 - journals.physiology.org
… hypoxia-induciblefactor (HIF)-1 during acute inflammation was investigated in experimental wounds. HIF-1α … HIF-1α protein was detectable in wound cells 1 and 5 days after injury. …
HX Zhang, JJ Yang, SA Zhang… - European Review for …, 2018 - europeanreview.org
… inflammation obstruction in airways. This study aims to explore the regulatory mechanism of hypoxia-inducible factor-1α (HIF-1α) in inflammatory response and progression of COPD. …