Influence of initial severity of depression on effectiveness of low intensity interventions: meta-analysis of individual patient data

P Bower, E Kontopantelis, A Sutton, T Kendrick… - Bmj, 2013 - bmj.com
… We describe an individual patient data meta-analysis of depression severity as a … of depression
severity). We split the data into five equally sized groups on the basis of the initial severity

Severity at baseline and onset of improvement in depression. Meta-analysis of imipramine and moclobemide versus placebo

HH Stassen, J Angst, A Delini-Stula - European psychiatry, 1994 - cambridge.org
… A crucial point in our analysis of efficacy of antidepressants was, as a matter of fact, the
analysis of premature withdrawals. Our findings indicate that initial severity of the disease may …

[HTML][HTML] Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration

I Kirsch, BJ Deacon, TB Huedo-Medina… - PLoS …, 2008 - journals.plos.org
… Yet, the efficacy of the antidepressants may also depend on the severity of initial depression
scores. The purpose of this analysis is to establish the relation of baseline severity and …

Initial severity of major depression and efficacy of new generation antidepressants: individual participant data metaanalysis

TA Furukawa, K Maruo, H Noma… - Acta Psychiatrica …, 2018 - Wiley Online Library
… baseline severity as … study aims to examine whether baseline severity modifies the efficacy
of various antidepressants for major depression through individual participant data (IPD) meta

Initial severity of depression and efficacy of cognitive–behavioural therapy: individual-participant data meta-analysis of pill-placebo-controlled trials

TA Furukawa, ES Weitz, S Tanaka… - The British Journal of …, 2017 - cambridge.org
… Aims To synthesise evidence regarding the influence of initial severity on efficacy of CBT …
major depression. Method A systematic review and an individual-participant data meta-analysis

A meta-analysis of depression severity and cognitive function

LM McDermott, KP Ebmeier - Journal of affective disorders, 2009 - Elsevier
… The overall findings of the present study, which suggest that severity of depressive symptoms
is … First, the findings suggest that severity of depression determines the nature of a patient's …

… depression severity as moderator of depression outcomes between cognitive behavioral therapy vs pharmacotherapy: an individual patient data meta-analysis

ES Weitz, SD Hollon, J Twisk, A Van Straten… - JAMA …, 2015 - jamanetwork.com
depression outcomes. However, we first analyzed the effects of treatment group on depression
outcomes while holding baseline severity constant. Posttreatment scores on the HAM-D …

Antidepressant drug effects and depression severity: a patient-level meta-analysis

JC Fournier, RJ DeRubeis, SD Hollon, S Dimidjian… - Jama, 2010 - jamanetwork.com
… we used the most inclusive sample analyzed in the original publication of each of the 6 …
initial severity and symptom change scores in ADM vs placebo, we conducted analyses of …

Does pretreatment severity moderate the efficacy of psychological treatment of adult outpatient depression? A meta-analysis.

E Driessen, P Cuijpers, SD Hollon… - Journal of consulting …, 2010 - psycnet.apa.org
Meta-Analyses This study assessed whether pretreatment depression severity is related
to … First, we conducted metaregression analyses to assess whether the mean pretreatment …

Initial depression severity and response to antidepressants v. placebo: patient-level data analysis from 34 randomised controlled trials

J Rabinowitz, N Werbeloff, FS Mandel… - The British Journal of …, 2016 - cambridge.org
… relationship between initial severity and antidepressant … severe depression rather than to
increased responsiveness to medication. We conducted both patient-level and meta-analysis of …