… Gelatinase zymography (3 days after operation) showed a minor activity of MMP-2/MMP-9
in noninjured nerves. Crush injury significantly elevated MMP-2/MMP-9 activity, and this …

… that MMP-9 can catabolize Aβ and MMP-2 is capable of Aβ degradation [61, 63]. Moreover,
… MMP-2 plays beneficial role in peripheral nerve regeneration during the late phase of injury. …

… diseases of the central nervous system to suppress neuroinflammation [14]. Therefore, we
hypothesized that TMP might suppress chronic constrictive injury (CCI)-induced MMP-2/9 from …

… nerve growth factor (NGF) levels. In this study, we investigated whether the inhibition of mature
NGF degradation, using a matrix metalloproteinase 2 and 9 (MMP-2/… tissue injury [8]. NGF …

… in a mouse model of olfactory nerve injury. This study used knockout mice to show an early
elevation of MMP-9 followed by a later, independent peak in MMP-2 activation. Other studies …

… The response of the adult mammalian central nervous system (CNS) to injury results in a
gliosis … inhibitor of metalloproteinase 2 (TIMP-2) inhibit MMP-2 that degrades collagen I and IV. …

… the mouse sciatic nerve, an upregulation of MMP-2 and MMP-9 with … Nerve injury (SNL)
causes an early but transient upregulation of MMP-9 in neurons, whereas in later stage, MMP-2 …

… Other works show that MMP-2 and MMP-9 promote axonal outgrowth in injured peripheral
and were more expressed during maturation of the scar tissue of injured adult spinal cord […

… (A) and the intensity of the bands of both pro- and active MMP-2 (B) increase after post-ganglionic
nerve crush. (C) β-Dystroglycan Western immunoblot in control and injured SCG. The …

… that elevated MMP-12 activity at the site of nerve injury can … Spinal nerves harvested from
rats euthanized 1 or 2 weeks … and histology staining or MMP-12 activity assay. Rats that …