过去一年中添加的文章,按日期排序

Epigenetic Mechanisms of Ikaros Mediated Tumor Suppression in B-Cell Acute Lymphoblastic Leukemia

A Richman - 2024 - scholarworks.uvm.edu
8 天前 - … genome DNA methylation to reveal a direct role of Ikaros in regulating DNA methylation
at genes where methylation … I provide an integrative, multi-scaled approach to uncover …

[HTML][HTML] Genetic insights into drug targets for sporadic Creutzfeldt-Jakob disease: Integrative multi-omics analysis

D Jiang, H Nan, Z Chen, WQ Zou, L Wu - Neurobiology of Disease, 2024 - Elsevier
10 天前 - … randomization, and colocalization analyses were employed to explore potential
therapeutic targets using expression, single-cell expression, DNA methylation, and protein …

Integrative Analysis of Whole Genome Bisulfite and Transcriptome Sequencing Reveals the Effect of Sodium Butyrate on Dna Methylation in the Differentiation of …

X Zhou, C Li, C Qu, Y Shi, CJ Li, X Kang - papers.ssrn.com
13 天前 - … However, the impact of butyrate on the DNA methylation of … effects of butyrate
treatment on DNA methylation status and its … -mediated DNA methylation on SMSC development. …

Integrative analysis of genomic and epigenomic regulation reveals miRNA mediated tumor heterogeneity and immune evasion in lower grade glioma

Z Yang, X Liu, H Xu, AE Teschendorff, L Xu, J Li… - Communications …, 2024 - nature.com
14 天前 - … In the present work, we performed a systematic integrative study for genome-wide
DNA methylation, copy number variation and miRNA expression data to identify mechanisms …

Update: The Role of Epigenetics in the Metabolic Memory of Diabetic Complications

Z Chen, V Malek, R Natarajan - American Journal of …, 2024 - journals.physiology.org
16 天前 - … changes in DNA methylation, histone methylation and acetylation at key genomic
loci … Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat Rev 671 …

Integrative multi-omics analyses identify molecular subtypes of head and neck squamous cell carcinoma with distinct therapeutic vulnerabilities

P Diao, Y Dai, A Wang, X Bu, Z Wang, J Li, Y Wu… - Cancer …, 2024 - aacrjournals.org
17 天前 - analyze multi-omics datasets spanning copy number variations, somatic mutations,
DNA methylation… The integrative model consistently identified three subgroups (IMC1-3) with …

ABSTRACT CITATION ID: NOAE064. 469 MDB-20. TOXICITY PROFILE OF TWO CHEMOTHERAPEUTIC REGIMENS ADOPTED FROM COG A9961 AND ACNS0331 …

MMH Elayadi, SM Elsayed - Neuro-oncology, 2024 - europepmc.org
19 天前 - Integrative analyses were adapted to incorporate a wide variety of sample-paired
datasets. Chromatin contact matrices generated from Hi-C allowed for the mapping of active/…

Comprehensive pan-cancer analysis reveals that C5orf34 regulates the proliferation and mortality of lung cancer

M Yang, Y Deng, Y Ma, C Song, Z Wu… - Functional & Integrative …, 2024 - Springer
21 天前 - … expression, we conducted comprehensive analyses of mutations and copy number
variations in the C5orf34 gene, along with DNA methylation alterations within the initiating …

Integrative Genetic Variation, DNA Methylation, and Gene Expression Analysis of Escitalopram and Aripiprazole Treatment Outcomes in Depression: A CAN-BIND-1 …

F Islam, A Lisoway, ES Oh, LM Fiori… - …, 2024 - thieme-connect.com
25 天前 - … This study explored the relationship among single nucleotide polymorphisms (SNPs),
DNA methylation (DNAm), and mRNA levels of four pharmacokinetic genes, CYP2C19, …

MDB-10. DIVERGENT MEDULLOBLASTOMA CHROMATIN STATES DISCLOSE KDM2B AS A NOVEL ONCOGENIC DEPENDENCY

R Tao, S Erkek, Y Matsui, B Xu, KS Smith, Q Gao… - Neuro …, 2024 - ncbi.nlm.nih.gov
30 天前 - Integrative bioinformatics coupled with CUT&RUN analysis revealed significant
enrichment of KDM2B, a histone lysine demethylase overexpressed in Group 4-MB, in gene …