… Although this result would suggest that the synergistic antiviral effect observed in cultures
treated with both IFN-β and IFN-γ is specific to SARS-CoV, we cannot exclude the possibility …

… These properties might facilitate improvement or recovery in patients with SARS-CoV-…
interferon beta-1a formulation (SNG001) in patients admitted to hospital with confirmed SARS-CoV…

… of IFN expression and cellular responses to IFNs. In this review, we describe the innate
sensing … of SARS-CoV-2 and the mechanisms used by SARS-CoV-2 to evade type I and III IFN …

… of SARS-CoV in cell culture can be strongly inhibited by pretreatment with interferon-beta. …
We investigated the inhibitory effect of type I and II IFNs on SARS-CoV multiplication in cell …

… pathogen of COVID-19, SARS-CoV-2, and host innate … SARS-CoV-2 induces overt but
delayed type-I interferon (IFN) responses. By screening 23 viral proteins, we find that SARS-CoV-…

… human interferon (IFN)-β 1a potently inhibits SARS coronavirus replication in vitro. … suggests
that IFN-β 1a may be effective as a treatment for SARS-CoV infections. As noted above, IFN-…

… SARS-CoV-2 to recombinant human interferons α and β (IFNα/β). Treatment with IFN-α or
IFN-… The EC 50 of IFN-α and IFN-β treatment is 1.35 IU/ml and 0.76 IU/ml, respectively, in Vero …

… inhibit the synthesis of type I interferon (IFN), but the … SARS-CoV could inhibit IFN-beta (IFN-β)
induced by poly(I:C) or Sendai virus. However, we found that N protein could not inhibit IFN…

… the interferon effects on SARS-CoV, … interferons on SARS-CoV-induced cytopathogenic
effects in Vero cells when the drugs were added after infection (1 h adsorption period). Interferon …

… SARS-CoV-2 NSP12 and IFN-β response. Using various strategies, we demonstrate SARS-CoV-2
NSP12 protein is not an IFN… could affect the readout of IFN-β promoter luciferase assay…