Tumor necrosis factor, its receptors and the connection with interleukin 1 and interleukin 6

P Brouckaert, C Libert, B Everaerdt, N Takahashi… - Immunobiology, 1993 - Elsevier
… Here, we will restrict ourselves to the effects of tumor necrosis factor (TNF), a key mediator
in two important activities of endotoxin viz. the antitumor effect and the shock-inducing effect. …

The biology of interleukin 1 and comparison to tumor necrosis factor

CA Dinarello - Immunology letters, 1987 - Elsevier
Tumor necrosis factor shares with IL-1 many of the systemic and local effects of IL-1; these
include fever, acute phase protein synthesis and sleep. Some of the in vitro effects of IL-…

Circulating interleukin 1 and tumor necrosis factor during inflammation

LL Moldawer, J Gelin, T Schersten… - American Journal of …, 1987 - journals.physiology.org
… It is proposed that interleukin 1 (IL I) and tumor necrosis factor (TNF) alpha play central roles
INTERLEUKIN 1 (IL 1) and tumor necrosis factor (TNF) alpha (cachectin) are two peptide …

Interleukin 1 and tumor necrosis factor

M Gowen - Cytokines and bone metabolism, 1992 - books.google.com
… Its close biological similarities with tumor necrosis factor (TNF) leads to a discussion in this
INTERLEUKIN-1 IL-1 exists as two related proteins with virtually identical actions on a wide …

The contribution of interleukin1 and tumor necrosis factor to periodontal tissue destruction

DT Graves, D Cochran - Journal of periodontology, 2003 - Wiley Online Library
Interleukin (IL)‐1 and tumor necrosis factor (TNF) represent proinflammatory cytokines that
stimulate a number of events which occur during periodontal disease. These include the …

Interleukin 1, tumour necrosis factor‐alpha (cachectin) and the pathogenesis of cancer cachexia

LL Moldawer, M Georgieff, K Lundholm - Clinical Physiology, 1987 - Wiley Online Library
… During inflammatory states, including active turnout growth, increased production of some
cytokines, including interleukin 1 and tumour necrosis factor-alpha (cachectin), have been …

Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon.

JS Pober, MA Gimbrone Jr, LA Lapierre… - … (Baltimore, Md.: 1950 …, 1986 - journals.aai.org
… For example, interleukin 1 (IL-1) and tumor necrosis factor (TNF), but not immune interferon
(IFN-7). cause the normally "anti-coagulant" HUVE cell surface to become procoagulant (1 0-…

Synergistic interactions between interleukin 1, tumor necrosis factor, and lymphotoxin in bone resorption.

P Stashenko, FE Dewhirst, WJ Peros… - Journal of immunology …, 1987 - journals.aai.org
… include IL 1 beta (pI 7), IL 1 alpha (pI 5), tumor necrosis factor (TNF), and lymphotoxin (LT).
Possible interaction between IL 1 beta, the major mediator with osteoclast-activating factor (…

Tumor necrosis factor and interleukin 1 alpha increase vascular endothelial permeability

JA Royall, RL Berkow, JS Beckman… - … of Physiology-Lung …, 1989 - journals.physiology.org
tumor necrosis factor induces procoagulant activity in cultured … and comparison with the
actions of interleukin 1. Proc. Natl. … Interleukin 1 and tumor necrosis factor stimulate human …

Interleukin 1 or tumor necrosis factor-alpha: which is the real target in rheumatoid arthritis?

JM Dayer - The Journal of rheumatology Supplement, 2002 - jrheum.org
… Much debate has focused on the relative importance of interleukin 1 (IL-1) and tumor
necrosis factor-α (TNF-α) in the pathophysiology of rheumatoid arthritis (RA). The production of …