Effect of interleukin10 on dendritic cell maturation and function

T De Smedt, M Van Mechelen… - European journal of …, 1997 - Wiley Online Library
… There is evidence that IL-10 inhibits immune responses by regulating APC function, … effect
on CD4+ T cells [7]. We tested whether IL-10 affected the accessory function of dendritic cells

Human dendritic cell responses to lipopolysaccharide and CD40 ligation are differentially regulated by interleukin10

C Buelens, V Verhasselt, D De Groote… - European journal of …, 1997 - Wiley Online Library
… and CD40 ligation are differentially regulated by interleukin-10 We evaluated the effects
of interleukin (1L)-10 on the maturation of human dendritic cells (DC) induced either by …

Interleukin10 prevents the generation of dendritic cells from human peripheral blood mononuclear cells cultured with interleukin‐4 and granulocyte/macrophage …

C Buelens, V Verhasselt, D De Groote… - European journal of …, 1997 - Wiley Online Library
… mononuclear cells cultured with interleukin-4 … of interleukin (1L)-10 on the differentiation of
dendritic cells (DC) obtained by culturing plastic-adherent peripheral blood mononuclear cells

Induction of interleukin-10 producing dendritic cells as a tool to suppress allergen-specific T helper 2 responses

S Schülke - Frontiers in immunology, 2018 - frontiersin.org
… anergy, regulatory T cells, or production of regulatory cytokines. Among the … DCs, interleukin
10 (IL-10) is a key regulatory cytokine limiting und ultimately terminating excessive T-cell

Interleukin-10 secretion differentiates dendritic cells from human liver and skin

S Goddard, J Youster, E Morgan, DH Adams - The American journal of …, 2004 - Elsevier
Liver dendritic cells (DCs), which may orchestrate the liver's unique immunoregulatory functions,
remain poorly characterized. We used a technique of overnight migration from pieces of …

Interleukin 10 inhibits T cell alloreaction induced by human dendritic cells

C Caux, C Massacrier, B Vanbervliet… - International …, 1994 - academic.oup.com
… In vitro, the primary activation of alloreactive T cells appears to be essentially mediated by
dendritic cells (DC) (9-12), which comprise a system of highly efficient antigen presenting cells

Interleukin-10 and the interleukin-10 receptor

KW Moore, R de Waal Malefyt… - Annual review of …, 2001 - annualreviews.org
… These chemokines are implicatedin the recruitment of monocytes, dendritic cells,
neutrophils, and T cells.Thus, IL-10 inhibits expression of most inducible chemokines that are …

… of Interleukin 10–Producing, Nonproliferating Cd4+ T Cells with Regulatory Properties by Repetitive Stimulation with Allogeneic Immature Human Dendritic Cells

H Jonuleit, E Schmitt, G Schuler, J Knop… - The Journal of …, 2000 - rupress.org
… The functional properties of dendritic cells (DCs) are strictly dependent on their … dendritic
cells to T cell clones. Intact protein is presented best by immature, epidermal Langerhans cells

Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10

E Martin, B O'Sullivan, P Low, R Thomas - Immunity, 2003 - cell.com
… Regulatory CD4 + T cells induced by the DCs transfer antigen-specific "infectious" tolerance
to primed recipients in an interleukin-10-dependent fashion. Thus CD40, regulated by RelB …

Interleukin-10–Treated Human Dendritic Cells Induce a Melanoma-Antigen–Specific Anergy in CD8+ T Cells Resulting in a Failure to Lyse Tumor Cells

K Steinbrink, H Jonuleit, G Muller… - Blood, The Journal …, 1999 - ashpublications.org
Dendritic cells (DC) are critically involved in the initiation of primary immune processes, …
the effect of interleukin-10 (IL-10)–treated human DC on the properties of CD8 + T cells that are …