Z Hu, S Li, X Song - Cytokine & growth factor reviews, 2021 - ncbi.nlm.nih.gov
… that cytokinestorm manifested by rapidly elevated IL-6 in a short time maybe the main cause of sudden death. All 8 patients with cytokinestorm … long-term cytokinestorm. We performed …
LYC Chen, RL Hoiland, S Stukas… - European …, 2020 - Eur Respiratory Soc
… controversies and demonstrate that cytokinestorm syndrome may play … cytokinestorm syndrome Critics of the COVID-CSS concept have claimed that “cytokinestorm has no definition” [6…
J Shekhawat, K Gauba, S Gupta, P Purohit… - Indian Journal of Clinical …, 2021 - Springer
… by CytokineStorm (CS). CS is marked by elevated levels of inflammatory cytokines, mainly interleukin-6 (IL-6), … Of these, IL-6 is found to be significantly associated with higher mortality. …
T Tanaka, M Narazaki, T Kishimoto - Immunotherapy, 2016 - Taylor & Francis
… ‘cytokinestorm’. This review focuses on the pathological role of IL-6 in a cytokinestorm and the therapeutic effect of IL-6 … Interleukin6 (IL-6) levels in the monitoring of surgical trauma. A …
A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
… to a hyperinflammatory state (“cytokinestorm”) followed by acute respiratory … cytokinestorm in its severest form has been marked by elevation of IL-6, IL-10, TNF-α, and other cytokines …
B Liu, M Li, Z Zhou, X Guan, Y Xiang - Journal of autoimmunity, 2020 - Elsevier
… The elevated inflammatory cytokines suggest that a cytokinestorm, also known as cytokine … We propose to utilize interleukin-6 (IL-6) blockade to manage COVID-19-induced CRS and …
B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
… is an urgent need to understand the cytokinestorm in COVID‐19. … cytokinestorm induced by COVID‐19. In addition, we suggest that the identification and treatment of the cytokinestorm …
F Coperchini, L Chiovato, M Rotondi - Frontiers in immunology, 2021 - frontiersin.org
… IL-6 induces a transcriptional inflammatory response through its binding to interleukin6 receptor, alpha (IL-6Rα) (30). IL-6 is involved in the promotion of the specific differentiation of …
S Douedi, M Chaudhri, J Miskoff - Annals of Thoracic Medicine, 2020 - journals.lww.com
… illness and produce a cytokinestorm associated with increased morbidity and … -interleukin-6 receptor monoclonal antibody, has been found to be effective in managing the cytokinestorm…