… The significant role of IL-6 in pathogenesis of COVID-19 was confirmed in a range of studies…
of IL-6 was increased in patients with severe COVID-19. Currently, IL-6 inhibitor therapeutics …

… 6 is an important marker of inflammation and can guide the clinicians in recognizing patients
with severe COVID… 6 to assist clinicians in early recognition of patients at risk for developing …

… In this systematic review and meta-analysis, we demonstrate that serum levels of IL-6 are
significantly elevated in the setting of severe Covid-19 disease. Meta-analysis of the available …

… In the context of COVID-19 pandemic and growing tensions … physicians to screen patients
with severe COVID-19 for … >5 days of prior disease duration, severe (ie requiring strictly over 6L/…

… change in IL‐6 can be used as a marker for disease monitoring in patients with severe
COVID‐19. … Sixty‐nine severe COVID‐19 patients were analyzed for disease monitoring. Elevated …

… the role of interleukin-6 (IL-6) in the pathogenesis, prognosis, and treatment of COVID-19
by comparing its effect on SARS-CoV and MERS cases. Increased levels of IL-6 comprise the …

… IL‐6 levels and severe COVID‐19, we … COVID‐19; if they contained patients with mild and
severe disease, or survivor and death groups; and if they reported sufficient details about IL‐6. …

… severe COVID-19 pneumonia and systemic hyperinflammation. Methods We conducted an
open-label study of sarilumab in severe COVID… markers and serum IL-6 levels). Sarilumab …

… After exclusion of patients requiring immediate intensive care unit (ICU) admission, we
analyzed risk factors for the combined endpoint progression to severe COVID-19 syndrome and/…

… ill COVID-19 patients with significantly elevated IL-6. In conclusion, CRS occurs in a large
number of patients with severe COVID-19, which is an important cause of death. IL-6 is the key …