… cytokine storms as well as coronavirus disease 2019 (COVID-19). Here, we highlight the …
contributions of IL-6 signaling to the pathogenesis of several types of cytokine storms and …

… to a hyperinflammatory state (“cytokine storm”) followed by acute respiratory … cytokine storm
in its severest form has been marked by elevation of IL-6, IL-10, TNF-α, and other cytokines …

… as a ‘cytokine storm’. This review focuses on the pathological role of IL-6 in a cytokine storm
and the therapeutic effect of IL-6 … of recombinant factor VIIa elicits interleukin 6 (IL-6) and IL-8 …

… by Cytokine Storm (CS). CS is marked by elevated levels of inflammatory cytokines, mainly
interleukin-6 (IL-6), … Of these, IL-6 is found to be significantly associated with higher mortality. …

… lethal unconstrained inflammatory cytokine storm, known as cytokine release syndrome (CRS). …
and how targeted inhibition of interleukin (IL)‑6 signaling may improve outcomes and the …

… that IL-6 plays a major role in the cytokine storm. The so-called COVID-19–related cytokine
storm … a strong induction of IL-6 secretion is observed (46, 47). The consequent high levels of …

… The elevated inflammatory cytokines suggest that a cytokine storm, also known as cytokine
… We propose to utilize interleukin-6 (IL-6) blockade to manage COVID-19-induced CRS and …

… response associated with cytokine storm syndrome, … The chronicization of the
hyperinflammatory cytokine storm in … pathogenesis mediated primarily by Interleukin-6, which is, …

… Corticosteroids are powerful drugs used to fight cytokine storm, but its side effects … cytokine
storm might be a perspective choice. IL-6 is thought to be a key mediator of cytokine storm…

… Similarly, blockade of trans-signalling while leaving classical signalling intact may prove
to be beneficial for patients experiencing “cytokine storms” from COVID-19 or CAR T-cell …