Elevated interleukin levels are associated with higher severity and mortality in COVID 19–a systematic review, meta-analysis, and meta-regression

E Yonas, I Alwi, R Pranata, I Huang, MA Lim… - Diabetes & Metabolic …, 2020 - Elsevier
Interleukin”. The inclusion criterion for the studies in this meta-analysis was are all studies that
reported interleukin (IL) levels … defined by the incidence of severe COVID 19 (patients with …

High serum levels of tumour necrosis factor‐α and interleukin‐8 in severe asthma: markers of systemic inflammation?

M Silvestri, M Bontempelli, M Giacomelli… - Clinical & …, 2006 - Wiley Online Library
… We showed high levels of sTNF-α in severe asthma suggesting an increased production
of this cytokine from the airways of severe asthmatics. Probably, the role of TNF-α in severe

[HTML][HTML] Elevated interleukin‐6 is associated with severity of COVID‐19: a meta‐analysis

J Zhu, J Pang, P Ji, Z Zhong, H Li, B Li… - Journal of medical …, 2021 - ncbi.nlm.nih.gov
… Our results indicate that elevated IL‐6 levels occur more often in severe and critically ill than
… the idea that IL‐6 levels positively correlate with COVID‐19 severity and risk of fatality. , 9 …

Relationship of interleukin-10 plasma levels to severity of injury and clinical outcome in injured patients

R Neidhardt, M Keel, U Steckholzer… - Journal of Trauma …, 1997 - journals.lww.com
Severe trauma is associated with a high incidence of infection, multiple organ dysfunction
syndrome (MODS), and adult respiratory distress syndrome (ARDS), which markedly influence …

Prognostic value of interleukin-18 and its association with other inflammatory markers and disease severity in COVID-19

H Satış, HS Özger, PA Yıldız, K Hızel, Ö Gulbahar… - Cytokine, 2021 - Elsevier
levels were remarkably higher in COVID-19 patients compared to healthy subjects with being
highest in severe … IL-18 serum concentrations were almost four-fold higher in patients with …

Serum profiles of interleukin-6, interleukin-8, and interleukin-10 in patients with severe and mild acute pancreatitis

T Berney, Y Gasche, J Robert, A Jenny, N Mensi… - Pancreas, 1999 - journals.lww.com
… of the tissue lesions observed in severe acute pancreatitis (7,27). In this study, serum
levels of PMNE were higher in cases with severe disease, corroborating earlier reports (28). …

Increased interleukin-6 levels associated with malaria infection and disease severity: a systematic review and meta-analysis

P Wilairatana, W Mala, GDJ Milanez, FR Masangkay… - Scientific Reports, 2022 - nature.com
… Differences in the mean IL-6 levels among patients with: (1) severe and non-severe malaria,
… with severe malaria had higher mean IL-6 levels than those with non-severe malaria [P = …

Circulating levels of interleukin-6 and interleukin-10, but not tumor necrosis factor-alpha, as potential biomarkers of severity and mortality for COVID-19: systematic …

W Udomsinprasert, J Jittikoon… - Journal of clinical …, 2021 - Springer
levels of inflammatory cytokines with severity and … levels of IL-6 and IL-10 in both patients
with severe COVID-19 and non-survivors, which confirm our notion that high circulating levels

[HTML][HTML] Evaluation of interleukin-6 and its association with the severity of disease in COVID-19 patients

S Bhandari, G Rankawat, A Singh… - Indian Journal of …, 2020 - journals.lww.com
… extremely high IL-6 levels are definitely at high risk of severe and … higher mortality.
SARS-CoV-2-infected patients with extremely elevated IL-6 levels are susceptible to develop severe

Elevated interleukin (IL)-6 as a predictor of disease severity among Covid-19 patients: a prospective cohort study

B Nikkhoo, M Mohammadi, S Hasani, N Sigari… - BMC Infectious …, 2023 - Springer
… related to the severity of the disease is one of the interests of physician and medical
researchers. We hypothesized that interleukin 6 serum level is associated with severe outcome. …