… RNA sequencing (scRNA-seq), the characterization of macrophage heterogeneity has …
macrophages driven by scRNA-seq technology and highlights the role of interstitial macrophages …

… In the lung, macrophages can be broadly defined as airspace macrophages (AMs) versus.
interstitial macrophages (IMs) based on the compartments in which they reside. During health…

… Three unique interstitial macrophages in the murine lung at steady state. Am J Respir Cell …
Lung interstitial macrophages can present soluble antigens and induce Foxp3 + regulatory T …

… distinct macrophage subpopulations using scRNA-Seq … healthy control macrophages into
SPP1 macrophages. Analysis … transcription factors regulate SPP1 macrophage differentiation. …

… tissue macrophages (ie, lung IM) in naive C57BL/6 female wild-type (WT) mice, we performed
scRNA-seq using … In addition, a second scRNA-seq experiment was performed through an …

… Few studies have examined lung interstitial macrophage (IM) molecular phenotypes after
being exposed to hypoxia in vivo at the single-cell level, even though macrophages contribute …

… Tissue-resident macrophages are a diverse … interstitial subset of CD169 + lung-resident
macrophages that are transcriptionally and developmentally distinct from alveolar macrophages (…

… Tissue-resident alveolar and interstitial macrophages and recruited macrophages are critical
players in innate immunity and maintenance of lung homeostasis. Until recently, assessing …

… Lung interstitial macrophages (IMs) and hypoxia are acknowledged to contribute to
pulmonary hypertension (PH). Yet few studies have examined IM molecular phenotypes after …

… 3, b, e, and f); hence, we refer to them as “alveolar macrophages.” Another cluster we call
“interstitial macrophages” (IMs) expressed lower levels of the classical AM markers including …