… the intestinal microbiota, and by chronic intestinal inflammation… breakdown of intestinal
homeostasis, leading to IBD and colitis-… roles for immune sensing in intestinal epithelial cells and …

… intestinal homeostasis, we subjected wild-type (WT), Casp1À/À, Casp12À/À, and AscÀ/À mice
to an experimental model of tissue injury and colitis. … to inflammation during colitis and that …

… effects in experimental colitis. The … intestinal homeostasis and intestinal inflammation
and suggest that strategies, that modulate type 1 IFN may be of therapeutic value for intestinal …

… of mice in both experimental colitis and intestinal wound healing … IBD and provide additional
insights how the activation of epithelial STAT3 by IL-22 regulates intestinal homeostasis and …

… in colon tissues from IBD patients, specifically … experimental colitis. On this basis, we propose
that ATG4B has a crucial role in intestinal homeostasis and plays a protective role in colitis. …

… We designed a screen to identify genes required for intestinal homeostasis. Third-generation
(G3) mutant mice were exposed to 1.5% (wt/vol) DSS in their drinking water for 7 d and …

… impacts immune homeostasis in the intestine. … in colitis, we challenged GPR81 −/− and
littermate control (WT) mice with 2.5% DSS, an experimental model of tissue injury and intestinal …

… of intestinal homeostasis 3,4 . These interactions are not only important for the pathogenesis
of IBD, but also essential for maintaining normal intestinal … In IBD and experimental colitis, …

… colitis. The loss of EPCR appeared to associate with increased disease index of the
experimental colitis in … sulfate sodium (DSS)-induced colitis, manifested by increased weight loss, …

… in experimental colitis. As a result we provide evidence for a relevant role of CPE for EEC
function and intestinal homeostasis. … contribute to new insights in the pathophysiology of IBD. …