On the role of Ca2+ in cerebral ischemic preconditioning

JS Tauskela, P Morley - Cell calcium, 2004 - Elsevier
ischemic preconditioning (IPC) represents a potent endogenous method of inducing tolerance
to otherwise lethal ischemia… the way that neuroscientists view Ca 2+ . Generally viewed as …

Ca2+ as a Mediator of Ischemic Preconditioning

H Miyawaki, M Ashraf - Circulation research, 1997 - Am Heart Assoc
… The main hypothesis of the present study was that Ca 2+ is an important intracellular trigger
or mediator of IPC. This hypothesis was formulated from our previous study, 14 in which …

Role of Intracellular Ca2+ in Activation of Protein Kinase C During Ischemic Preconditioning

K Node, M Kitakaze, H Sato, T Minamino… - Circulation, 1997 - Am Heart Assoc
… plays an important role in ischemic preconditioning. Given that protein kinase … intracellular
Ca 2+ concentration ([Ca 2+ ] i ) and that myocardial ischemia and reperfusion increase [Ca 2

Post‐ischemic brain damage: effect of ischemic preconditioning and postconditioning and identification of potential candidates for stroke therapy

G Pignataro, A Scorziello, G Di Renzo… - The FEBS …, 2009 - Wiley Online Library
… As ischemic preconditioning activates intracellular biological responses prior to a potential …
Another important player able to modulate intracellular Ca 2+ homeostasis during ischemia is …

Ischemic preconditioning: emerging evidence, controversy, and translational trials

S Sanada, M Kitakaze - International journal of cardiology, 2004 - Elsevier
… may be closely associated with transient changes of intracellular Ca 2+ during a brief period
of ischemia. While investigating the responsible subtype(s) of PKC in a dog model (Fig. 1) …

Exogenous nitric oxide triggers classic ischemic preconditioning by preventing intracellular Ca2+ overload in cardiomyocytes

O Rickover, T Zinman, D Kaplan, A Shainberg - Cell Calcium, 2008 - Elsevier
… the early phase of ischemic preconditioning is controversial, … NO in classic ischemic
preconditioning on cultured neonatal … intracellular calcium overload, which occurs during ischemia

Ischemic and anesthetic preconditioning reduces cytosolic [Ca2+] and improves Ca2+responses in intact hearts

J An, SG Varadarajan, E Novalija… - American Journal of …, 2001 - journals.physiology.org
… Like ischemic preconditioning (… extracellular Ca 2+ concentration ([Ca 2+ ] o ). To assess
differences in association between cyto[Ca 2+ ] and contractility before and after ischemia, [Ca 2

Intracellular free calcium and mitochondrial membrane potential in ischemia/reperfusion and preconditioning

KV Ylitalo, A Ala-Rämi, EV Liimatta… - Journal of molecular and …, 2000 - Elsevier
… has been implicated in ischemic preconditioning. As mitochondria possess an effective Ca2+
… time-averaged intracellular free calcium and the mitochondrial membrane potential during …

Calcium-sensing receptor: a sensor and mediator of ischemic preconditioning in the heart

J Sun, E Murphy - American Journal of Physiology-Heart …, 2010 - journals.physiology.org
… plays a cardioprotective role in ischemic preconditioning (IPC). Hearts from … extracellular
Ca 2+ , but also the local metabolic environment (3). In response to binding of extracellular Ca 2

Mechanism of preconditioning. Ionic alterations.

C Steenbergen, ME Perlman, RE London… - Circulation …, 1993 - Am Heart Assoc
… for intracellular Ca2' concentration and intracellular pH did show significant differences
between untreated and preconditioned hearts (for intracellular Ca2+ … in ischemic preconditioned