Calcium preconditioning elicits strong protection against ischemic injury via protein kinase C signaling pathway

H Miyawaki, X Zhou, M Ashraf - Circulation research, 1996 - Am Heart Assoc
… In summary, our results indicate that CPC offers strong protection against ischemic injury
initiating multiple intracellular signaling pathways leading to attenuation of ischemic injury. …

Calcium-sensing receptor: a sensor and mediator of ischemic preconditioning in the heart

J Sun, E Murphy - American Journal of Physiology-Heart …, 2010 - journals.physiology.org
… a cardioprotective role in ischemic preconditioning (IPC). … (four cycles of 5 min of global
ischemia and 5 min of reperfusion); or … min of no-flow global ischemia and 120 min of reperfusion. …

Role of increased cytosolic free calcium concentration in myocardial ischemic injury

C Steenbergen, TA Fralix, E Murphy - Basic research in cardiology, 1993 - Springer
… of preconditioning on ischemic injury and its ability to abolish the protective effect of
preconditioning … If ionic alterations play an important role in ischemic injury, then there should be a …

Calcium-activated potassium channel triggers cardioprotection of ischemic preconditioning

CM Cao, Q Xia, Q Gao, M Chen, TM Wong - Journal of Pharmacology and …, 2005 - ASPET
… the effects of preconditioning with ischemic insults on injury induced by ischemia/reperfusion …
of blockade of mPTP on cardioprotective effects of ischemic insults or activation of the K Ca …

[HTML][HTML] Cardiac preconditioning with calcium: clinically accessible myocardial protection

DR Meldrum, JC Cleveland Jr, BC Sheridan… - The Journal of Thoracic …, 1996 - Elsevier
… To study this, exogenous CaCl 2 was administered as a preconditioning stimulus before
ischemia-reperfusion to determine the following: (1) whether preischemic CaCl 2 administration …

Calcium preconditioning inhibits mitochondrial permeability transition and apoptosis

M Xu, Y Wang, K Hirai, A Ayub… - American Journal of …, 2001 - journals.physiology.org
… inhibition abolished the salutary effect of Ca 2+ preconditioning in the human myocardium. …
calcium preconditioning (CPC) conferred cardioprotection against ischemia-reperfusion injury

Calcium preconditioning in human myocardium

BS Cain, DR Meldrum, MD Xianzhong Meng… - The Annals of thoracic …, 1998 - Elsevier
… We postulated that Ca 2+ preconditioning confers ischemic tolerance to human myocardium
… 2+ preconditioning, we previously have reported that ischemic preconditioning increased …

The neuroprotective mechanism of brain ischemic preconditioning

X Liu, R Sheng, Z Qin - Acta Pharmacologica Sinica, 2009 - nature.com
… be triggered by cytoplasmic calcium overload, the NMDA receptor mediates rapid calcium
adaption in preconditioning that may alleviate the cell damage caused by calcium overload. …

Post‐ischemic brain damage: effect of ischemic preconditioning and postconditioning and identification of potential candidates for stroke therapy

G Pignataro, A Scorziello, G Di Renzo… - The FEBS …, 2009 - Wiley Online Library
… Regarding calcium homeostasis during ischemic preconditioning, the results of in vivo … in
mitochondrial calcium sequestration in CA1 hippocampal neurons after preconditioning [55]. In …

Ischemic preconditioning: nearly two decades of research. A comprehensive review

A Eisen, EZ Fisman, M Rubenfire, D Freimark… - Atherosclerosis, 2004 - Elsevier
… 3) Calcium—the role of calcium in preconditioning is also unclear. Calcium l-type channel
blockade prevents ischemic preconditioning in human myocardium [66], whereas no …