Sodium glucose co-transporter 2 (SGLT2) inhibition via dapagliflozin improves diabetic kidney disease (DKD) over time associatied with increasing effect on the gut …

J Wu, Y Chen, H Yang, L Gu, Z Ni, S Mou… - Frontiers in …, 2023 - frontiersin.org
… Diabetic kidney disease (DKD) is one of the most common chronic kidney diseases globally,
with growing incidence and prevalence (1), as 30% to 40% of patients with diabetes will …

Obesity and effects of dapagliflozin on cardiovascular and renal outcomes in patients with type 2 diabetes mellitus in the DECLARE–TIMI 58 trial

K Oyama, I Raz, A Cahn, J Kuder… - European heart …, 2022 - academic.oup.com
disease (CAD), heart failure (HF), stroke, other cardiovascular (CV) diseases, and diabetic
kidney disease. … fibrillation (AF) as well as kidney disease in part through its influence on the …

The Effect of Dapagliflozin on Rate of Kidney Function Decline in Patients with CKD: A Prespecified Analysis from the DAPA-CKD Trial: FR-OR51

HJL Heerspink, N Jongs, GM Chertow… - Journal of the …, 2021 - journals.lww.com
… : Dapagliflozin reduced the risk of kidney failure in patients with chronic kidney disease (…
This pre-specified analysis assessed the effect of dapagliflozin on the rate of change in …

Dapagliflozin reduces albuminuria over 2 years in patients with type 2 diabetes mellitus and renal impairment

P Fioretto, BV Stefansson, E Johnsson, VA Cain… - Diabetologia, 2016 - Springer
… long-term effects of dapagliflozin on urinary … kidney disease (CKD) and increased albuminuria
(≥3.4 mg/mmol). Patients were randomised to dapagliflozin 10 mg (n = 56), dapagliflozin

Short-term dapagliflozin administration in autosomal dominant polycystic kidney disease—a retrospective single-arm case series study

F Morioka, S Nakatani, H Uedono, A Tsuda… - Journal of Clinical …, 2023 - mdpi.com
… that they have heart and kidney protective effects in chronic kidney disease (CKD) patients
… the Dapagliflozin in Patients with Chronic Kidney Disease (DAPA-CKD) trial, dapagliflozin

The Association between Dapagliflozin Use and the Risk of Post-Contrast Acute Kidney Injury in Patients with Type 2 Diabetes and Chronic Kidney Disease: A …

T Liu, X Jian, L Li, S Chu, Z Fan - Kidney and Blood Pressure Research, 2023 - karger.com
… aimed to investigate the effect of dapagliflozin in preventing post-contrast acute kidney
injury (PC-AKI) in patients with type 2 diabetes (T2DM) and chronic kidney disease (CKD) who …

Dapagliflozin and cardiac, kidney, and limb outcomes in patients with and without peripheral artery disease in DECLARE-TIMI 58

MP Bonaca, SD Wiviott, TA Zelniker, O Mosenzon… - Circulation, 2020 - Am Heart Assoc
… , and kidney outcomes, and have a consistent benefits for CV death/HHF and progression
of kidney disease with dapagliflozin. … pattern of incremental risk observed with dapagliflozin. …

[HTML][HTML] Use of dapagliflozin in patients with advanced diabetic kidney disease

HS Park, YJ Jung, DY Lee, KH Moon… - Kidney Research and …, 2018 - ncbi.nlm.nih.gov
… We report five cases in which the SLGT2 inhibitor dapagliflozindapagliflozin for weight
reduction and glycemic control was worthwhile. We started dosing with 10 mg of dapagliflozin, …

Dapagliflozin Alleviates Diabetic Kidney Disease via Hypoxia Inducible Factor 1α/Heme Oxygenase 1-Mediated Ferroptosis

Y Wang, D Chang, M Zhao, M Chen - Antioxidants & Redox …, 2024 - liebertpub.com
… To explore the underlying mechanisms of ferroptosis-ameliorating effects of dapagliflozin
in diabetic kidney, kidney cortical tissues of mice were isolated for metabolomic analysis (…

Effects of dapagliflozin on volume status when added to renin–angiotensin system inhibitors

MK Eickhoff, CCJ Dekkers, BJ Kramers… - Journal of clinical …, 2019 - mdpi.com
… of six to 12 weeks of treatment with SGLT2 inhibitor dapagliflozin compared to placebo on
… albuminuric kidney disease. In addition, we aimed to characterize the effects of dapagliflozin