… kidney development, and the mechanisms of kidney regeneration. The complexity of the
genetic systems that are engineered for lineage tracing … attention in lineage tracing studies must …

… repair after AKI and their long-term consequences is critical to kidney health. The authors
used lineage tracing of cycling cells and single-nucleus multiomics (profiling transcriptome and …

… lineage-tracing methods focusing on the mouse model system and consider the impact of
these methods on our understanding of kidney … gene that is induced by kidney injury (Ngal) to …

… in a murine AKI model, the unilateral ischemia-reperfusion injury (IRI). For lineage tracing,
we analyzed the kidneys using single-cell profiling during disease development at various …

… Developing new therapeutic approaches to treat acute kidney injury requires a detailed …
Lineage tracing to determine origin of epithelial cells after kidney repair. Genetically labeled …

… regenerate medullary tubules following severe injury. These data also suggest that progenitor
cell pools and repair of kidney injury is regionally specific within the kidney. It should be …

… Recently, a single-nucleus multiomics technique has been adopted in Cre-loxP-based
conventional lineage tracing to depict the cellular transition upon acute kidney injury and profile …

… genomic lineage tracing approaches. Finally, we discuss how these cutting-… lineage
tracing techniques might be applied to kidney research. Established genetic lineage tracing …

… : Acute tubular injury accounts for the most common intrinsic cause for acute kidney injury
(… as a uniform reaction of tubule cells triggered by injury. Our group was the first to identify an …

… the changes in cellular fate that can occur during kidney injury. With the advent of single-cell …
Genetic lineage tracing in mouse has informed our understanding of mammalian kidney …