… -induced IFN-λ expression occurs faster than IFN-induced IFN-λ expression strongly … IFN-λ
gene promoters can be activated by a broader set of transcription factors than the type I IFN …

… I IFN (IFNα and IFNβ) and type III IFN [interferon lambda (IFNλ)]. Type I and type III IFNs
signal to surrounding cells via distinct receptors to induce activation of the JAK–STAT pathway …

… -one interferon’, 1 led to the discovery and characterization of the interferon lambda (IFN-λ) …
This is a new family of interferons related to both the IL-10 family of ligands and the Type-I …

… IFN-λs act by binding to the heterodimeric IFN-λ receptor (IFNLR), activating a STAT
phosphorylation-dependent signaling cascade. Thereby hundreds of IFN-… the IFN-λ …

… of the International Cytokine and Interferon Society on the basis of the sequence similarity
between IFN-λ4 and other IFN-λ proteins, as well as evidence that IFN-λ4 can induce antiviral …

… Lambda interferon (IFN-λ) induces an intracellular IFN-α/β-like antiviral response through
a … distinct from the IFN-α/β receptor. We therefore determined the ability of IFN-λ to inhibit …

… novel family of cytokines related to type-1 interferons, the lambda interferons (IFN-λ1/2/3). A
… IFN-λ family members, such as their anti-viral and growth inhibition effects, 1, 7 where IFN-λ …

… Interferon lambda (IFN-λ) is a member of the class II cytokine family, and like the other
members of this family, they are small helical proteins. Since their discovery significant efforts …

… Here, we review the structure of IFN-λ and its relation to the other members of the class II
cytokines. Further, we analyze the structural differences between the tree human isoforms of …

… The discovery of the interferon-lambda (IFN-λ) family has considerably contributed to …
interferon not only in viral infections but also in cancer. IFN-λ proteins belong to the new type III IFN …