… of these cells is orchestrated into specific subprograms and gene expression patterns,
suggesting that leukemic cell differentiation represents a highly coordinated set of events that lead …

… Aberrant expression of these factors interferes with differentiation events and has a role in
the pathogenesis of AML through superactivation or (dominant negative) repression of genes …

We analyzed the rearrangement and expression of T-cell receptor (TCR) genes, including
the recently identified TCR delta gene, in 21 patients with T-lineage leukemia/lymphoma. …

… Terminal cell differentiation of HL-60 promyelocytic leukemia cells results when they are
continuously exposed to retinoic acid. This process involves an intermediate regulatory state, …

… This review will address the molecular mechanisms underlying cell transformation in T-cell
acute lymphoblastic leukemia (T-ALL) and how these oncogenic events reveal the functions …

… in the study of pro-adipocyte differentiation [32]. With this … differentiation is an all-or-none
event initiated during a particular phase of the cell cycle which is likely to occur in relation to cell …

… monocytic cell line THP-1 throughout a time course of growth arrest and differentiation. …
Our results indicate that cellular states are constrained by complex networks involving both …

… differentiation of HL60 cells into mature granulocytes is an all-or-none event, whereby the
probability of each cell to differentiate … several other studies involving leukemic cells (Alder et al…

… cellular events during hepatocarcinogenesis illustrate that cancers may arise from cells at
various stages of differentiation … in treatment of acute promyelocytic leukemia and the ability of …

… differentiation of myeloid leukemic cells by 1,25(OH) 2 D 3 . This hypothesis also implies that
signaling events … maximal or terminal differentiation of myeloid leukemic cells. In support of …