Contribution of monocytes and macrophages to the local tissue inflammation and cytokine storm in COVID-19: Lessons from SARS and MERS, and potential …

A Jafarzadeh, P Chauhan, B Saha, S Jafarzadeh… - Life sciences, 2020 - Elsevier
… Despite some differences in the cytokine patterns, it seems that the cytokine storm plays a …
by recruiting leukocytes in the lungs [37].In COVID-19, the infiltrated leukocytes in alveoli were …

[PDF][PDF] Treatment of the Cytokine Storm in COVID-19

B Halacli, A Topeli - J Crit Intensive Care, 2020 - researchgate.net
… ABSTRACT Cytokine storm has been proposed as the basis of the … Cytokine storm,
generally known as excessive or uncontrolled release of especially proinflammatory cytokines, …

Cytokine storm and probable role of immunoregulatory drugs in COVID-19: a comprehensive review

A Sadeghzadeh-Bazargan, E Behrangi… - Iranian Journal of …, 2020 - iranjd.ir
… and TNF alpha; these changes are more prominent among those … through the recruitment
of leukocytes to the involved organ. Any … Since it is postulated that the cytokine storm may be …

[HTML][HTML] Hazards of the cytokine storm and cytokine-targeted therapy in patients with COVID-19

M Quirch, J Lee, S Rehman - Journal of medical Internet research, 2020 - jmir.org
… The aim of this paper is to study the cytokine storm response in SARS-CoV-2 and to explore
the early treatment options for patients who are critically ill with the coronavirus disease (…

The potential role of cytokine storm pathway in the clinical course of viral respiratory pandemic

G Murdaca, F Paladin, A Tonacci, S Isola, A Allegra… - Biomedicines, 2021 - mdpi.com
… of coagulation changes in cytokine storm patients has … several proinflammatory cytokines
implicated in the cytokine storm. … cytokine storm. The alteration of T cell functions, which heralds …

[PDF][PDF] Oxidized albumin triggers a cytokine storm in leukocytes through p38 Mitogen‐Activated protein kinase: role in systemic inflammation in decompensated …

J Alcaraz‐Quiles, M Casulleras, K Oettl, E Titos… - …, 2018 - Wiley Online Library
… HNA1 induces a cytokine storm in peripheral human leukocytes. (AD) Cytokine levels of
proinflammatory (IL-1β, IL-6, TNF-α, and IL-1α), anti-inflammatory (IL-1ra and IL-10), …

[HTML][HTML] Hematological changes in SARS-COV-2 positive patients

M Urbano, E Costa, C Geraldes - Hematology, transfusion and cell therapy, 2022 - Elsevier
… Results: Patients requiring the intensive care unit (ICU) present an increase in leukocytes
-COV-2-associated cytokine storm, as the IL-6 promotes the generation of megakaryocytes …

Lung under attack by COVID-19-induced cytokine storm: pathogenic mechanisms and therapeutic implications

C Pelaia, C Tinello, A Vatrella… - Therapeutic …, 2020 - journals.sagepub.com
… and activation of leukocytes, as well … cytokine storm and cytokine dysregulation lead to
remarkable pathological consequences. Indeed, the cytokine storm elicits immunological changes

Review on therapeutic targets for COVID-19: insights from cytokine storm

ML de Mélo Silva Júnior, LMA de Souza… - Postgraduate …, 2021 - academic.oup.com
leukocytes that release cytokines (notably IL-1, IL-6 and TNF) and induce tissue damage and
cell death, which leads to a vicious cycle of inflammation (cytokine storm) … to cytokine storm) …

Highways to hell: Mechanism-based management of cytokine storm syndromes

SW Canna, RQ Cron - Journal of Allergy and Clinical Immunology, 2020 - Elsevier
… devoted to cytokine storm syndromes (CSSs) was published in 2019, the world has changed
… Likewise, the utility of a broad term such as “cytokine storm” is that it reflects a convergence …