Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene

A Caspi, K Sugden, TE Moffitt, A Taylor, IW Craig… - Science, 2003 - science.org
… However, we found that the moderation of life stress on depression was specific to a
polymorphism in the 5-HTT gene, because this effect was observed regardless of the individual's …

Sensitizing effect of early adversity on depressive reactions to later proximal stress: Moderation by polymorphisms in serotonin transporter and corticotropin releasing …

LR Starr, C Hammen, CC Conway… - Development and …, 2014 - cambridge.org
stressors later in life (an environment–environment [ExE] interaction), and whether this “stress
sensitization” pattern in turn is moderated by … to sensitivity to stress: a polymorphism in the …

… life events, perceived stress, and 12-month course of geriatric depression: Direct effects and moderation by the 5-HTTLPR and COMT Val158Met polymorphisms

AS Zannas, DR McQuoid, DC Steffens, GP Chrousos… - Stress, 2012 - Taylor & Francis
… questions remain about the effects of stress on the course of geriatric … stress and change in
stress is associated with course of geriatric depression and (2) to test whether polymorphisms

BDNF Val66Met polymorphism, life stress and depression: A meta-analysis of gene-environment interaction

M Zhao, L Chen, J Yang, D Han, D Fang, X Qiu… - Journal of affective …, 2018 - Elsevier
… We found evidence that supported the hypothesis that BDNF Val66Met polymorphism
moderated the relationship between stress and depression, despite the fact that many included …

Associations between the COMT Val/Met polymorphism, early life stress, and personality among healthy adults

KF Hoth, RH Paul, LM Williams… - Neuropsychiatric …, 2006 - Taylor & Francis
… COMT polymorphism and … moderating effects of sex and early life stress on these relationships.
The results provide weak support for an association between the COMT polymorphism

Exploration of the moderating effects of physical activity and early life stress on the relation between brain-derived neurotrophic factor (BDNF) rs6265 variants and …

CT Soler, SH Kanders, S Olofsdotter, S Vadlin… - Genes, 2022 - mdpi.com
… In this study, we explored the relation between BDNF rs6265 polymorphism and childhood
stress, as well as the moderating effect of physical activity in relation to depressive symptoms …

Moderator effects of life stress on the association between MAOA-uVNTR, depression, and burnout

T Plieger, M Melchers, A Felten, T Lieser… - …, 2019 - karger.com
… More interesting, as it was the actual aim of the present study and has not been shown
before, is the combined influence of the MAOA-uVNTR polymorphism and life stress on …

Moderation of adult depression by a polymorphism in the FKBP5 gene and childhood physical abuse in the general population

K Appel, C Schwahn, J Mahler, A Schulz… - …, 2011 - nature.com
… Cerebrospinal fluid corticotropin-releasing factor and perceived early-life stress in depressed
… Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. …

Genetic moderation of stress effects on corticolimbic circuitry

R Bogdan, D Pagliaccio, DAA Baranger… - …, 2016 - nature.com
Stress exposure is associated with individual differences in corticolimbic structure and function
that often mirror patterns observed in psychopathology. Gene x environment interaction …

The 5‐HTTLPR polymorphism moderates the effect of stressful life events on drinking behavior in college students of African descent

HR Kranzler, D Scott, H Tennen, R Feinn… - American Journal of …, 2012 - Wiley Online Library
… Men showed a main effect of past-year stressful events on both drinking … or moderator
effects of genotype. In women, the S′ allele moderated the impact of past-year life stressors on …