… Here, we have investigated the mechanisms of protective immunity induced by immunization
… -dependent immune responses that mediate sterile protective immunity against liver-stage …

… the blood stage. In this review, we will briefly discuss the unique nature of the liver and how
… + T cells as being necessary for protective immunity during liver stage infection. We will also …

… play a major role in protective immunity against pre-erythrocytic stages of malaria parasites.
… -erythrocytic stages of Plasmodium. These T cells inhibit parasite development in the liver, …

… immunisation abrogated the acquisition of protection. Interestingly, protection was directed
not only against the liver stages but also against the blood stage parasites. This is one of the …

… full protection against subsequent challenge with infectious sporozoites in both animal models
of malaria and in human volunteers (12). The protective immunity that is … stage (13). Such …

… EErads in maintaining stage-specific protective immunity, the antimalarial drug primaquine,
which has been shown to eliminate not only rapidly dividing liver-stage parasites (18) but …

… Whether immunity to an intracellular eukaryotic parasite such as the liver stage of … In this
study, we explore the role of CD40 in generating a protective immune response during primary …

… protective immunity against pre-erythrocytic stage malaria by considering the humoral and
T cell-mediated immune … and liver stages of the infection where the induction of sterilizing …

… The protection induced by this immunization protocol proved to be very effective. Induction
of this protective immunity depended on the presence of liver stage … abrogated protection. …

… liver stage antigens. Since immunization with IRR SPZ provides potent protective immunity,
one appoach is to limit the investigation to antigens that are present at the latest stage of …