Distinguishing features of Long COVID identified through immune profiling

J Klein, J Wood, JR Jaycox, RM Dhodapkar, P Lu… - Nature, 2023 - nature.com
long COVID were enrolled in a cross-sectional study that included multidimensional immune
… to identify biological features associated with long COVID. Marked differences were noted …

[HTML][HTML] Immune profiling of COVID-19: preliminary findings and implications for the pandemic

HT Maecker - Journal for immunotherapy of cancer, 2021 - ncbi.nlm.nih.gov
COVID-19, this review will provide an overview of COVID-19 immune profiling in general. …
studies to find immune predictors of patients who will develop ‘long COVID-19’ or postacute …

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

…, AC Huang, LA Vella, UPenn COVID Processing Unit†… - Science, 2020 - science.org
… With the use of deep immune profiling, we identified three immunotypes in hospitalized
COVID-19 patients: (i) robust activation and proliferation of CD4 T cells, relative lack of cT FH …

Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19

ER Mann, M Menon, SB Knight, JE Konkel… - Science …, 2020 - science.org
… We undertook longitudinal immune profiling on both whole blood and peripheral blood …
peak of the COVID-19 pandemic in the United Kingdom. Here, we report key immune signatures …

Longitudinal immune profiling reveals distinct features of COVID-19 pathogenesis

ER Mann, M Menon, SB Knight, JE Konkel, C Jagger… - medRxiv, 2020 - medrxiv.org
… and is characterised by an exaggerated immune response, the specific components of which
… a longitudinal immune profiling study in hospitalised patients during the peak of the COVID-…

Deep immune profiling reveals early-stage and highly coordinated immune responses in mild COVID-19 patients

CM Capelle, S Cire, O Domingues, I Ernens, F Hedin… - medRxiv, 2021 - medrxiv.org
… cell responses are crucial for guiding the development of a protective adaptive immune
response at later stage, which is key for a long-term favorable outcome in non-hospitalized mild …

Single-cell immune profiling reveals distinct immune response in asymptomatic COVID-19 patients

XN Zhao, Y You, XM Cui, HX Gao, GL Wang… - Signal transduction and …, 2021 - nature.com
immune profiles in asymptomatic COVID-19 patients and highlight the difference of immune
… The specific signatures in asymptomatic patients will increase understanding of COVID-19 …

Comprehensive immune profiling reveals CD56+ monocytes and CD31+ endothelial cells are increased in severe COVID-19 disease

TS Dutt, SM LaVergne, TL Webb, BA Baxter… - The Journal of …, 2022 - journals.aai.org
… response dysregulation plays a key role in severe acute respiratory syndrome coronavirus
immune and endothelial blood cell profiles of patients with coronavirus disease 2019 (COVID-…

High-dimensional immune profiling by mass cytometry revealed immunosuppression and dysfunction of immunity in COVID-19 patients

W Wang, B Su, L Pang, L Qiao, Y Feng… - Cellular & molecular …, 2020 - nature.com
… Here, we profiled immune cellular components using mass … = 12) and a varying number of
COVID-19 patients with different clinical … Table 2) against 18 immune cell surface markers and …

[HTML][HTML] Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions

D Mathew, JR Giles, AE Baxter, AR Greenplate, JE Wu… - BioRxiv, 2020 - ncbi.nlm.nih.gov
… during COVID-19 disease, the immune characteristics of this response were heterogeneous.
By deep immune profiling, we identified three immunotypes in hospitalized COVID-19 …