Epigenetic clocks

AM Binder, S Horvath - Epigenetic Epidemiology, 2022 - Springer
… To track longitudinal variation in risk profile, epigenetic clocks … High reliability is indicated
by consistent epigenetic age … With the expansion of longitudinal studies of epigenetic age, …

Development of a novel epigenetic clock resistant to changes in immune cell composition

A Tomusiak, A Floro, R Tiwari, R Riley, H Matsui… - bioRxiv, 2023 - biorxiv.org
… to what extent epigenetic clocks are tracking a cell-autonomous or, conversely, a cell-ensemble
phenomenon 99 . Our data provide evidence that current epigenetic clocks represent a …

Epigenetic clocks in neurodegenerative diseases: a systematic review

T Yang, Y Xiao, Y Cheng, J Huang, Q Wei… - Journal of Neurology …, 2023 - jnnp.bmj.com
… to identify eligible studies reporting epigenetic clocks in several … the clinical utility of 11
epigenetic clocks (based on blood and … longitudinal population studies, due to multiple epigenetic

Reversal of epigenetic aging and immunosenescent trends in humans

GM Fahy, RT Brooke, JP Watson, Z Good… - Aging cell, 2019 - Wiley Online Library
… The specific epigeneticclocks” chosen for use in this study were those derived by Horvath
(… We used linear mixed-effects regression to properly account for the longitudinal nature of the …

[HTML][HTML] A common epigenetic clock from childhood to old age

A Freire-Aradas, L Girón-Santamaría… - Forensic Science …, 2022 - Elsevier
epigenetic clock covering the whole lifetime of a person, inter-individual variability should be
also considered. Since epigenetics … In the present study, a common epigenetic clock for all …

[HTML][HTML] What makes clocks tick? Characterizing developmental dynamics of adult epigenetic clock sites

RH Mulder, A Neumann, JF Felix, M Suderman… - bioRxiv, 2024 - ncbi.nlm.nih.gov
… Second, to be able to make relevant comparisons with our longitudinal DNAm set in in
childhood, we (ii) only selected epigenetic clocks that have been based on human material and (iii…

Epigenetic biomarkers of aging

ME Levine - Biomarkers of Human Aging, 2019 - Springer
… That being said, it is important to point out that nearly all of the applications of the
epigenetic clocks have been done in cross-sectional, rather than longitudinal data. Thus, the …

The role of epigenetic clocks in explaining educational inequalities in mortality: A Multicohort study and meta-analysis

G Fiorito, S Pedron, C Ochoa-Rosales… - The Journals of …, 2022 - academic.oup.com
… We measured epigenetic age from blood DNAm, known as epigenetic clocks. We considered
4 epigenetic clock biomarkers, namely Horvath’s and Hannum’s DNAmAge, Levine’s …

Epigenetic clocks in the pediatric population: when and why they tick?

J Wang, WH Zhou - Chinese Medical Journal, 2021 - mednexus.org
… It is currently well established that epigenetic clocks, composed of … to systematically summarize
the epigenetic clocks in the … a longitudinal analysis measuring DNAm by Horvath clock in …

Epigenetic clock and methylation studies in vervet monkeys

AJ Jasinska, A Haghani, JA Zoller, CZ Li, A Arneson… - GeroScience, 2022 - Springer
… We tested the performance of the vervet blood clock in longitudinal blood samples from 14
individuals collected at two different time points. In these samples, we correlated the changes …