… recognition of protein antigens is predominantly mediated by four to six complementarity-determining
regions (CDRs), which are the variable loops at the tip of each Fab. The relatively …

… Natural and synthetic immunogens containing V3 sequences elicit neutralizing immune …
antibodies have been mapped to the V3 region, and one of these monoclonal antibodies was …

… mode of interaction with V3, driven by contact residue requirements, may restrict the antibody
… access for antibodies with cross-neutralizing activity compared to antibodies that neutralize …

… loop of foot-and-mouth disease virus (FMDV), complexed with the Fab fragment of a neutralizing
monoclonal antibody … complementarity determining regions of the antibody molecule. …

… reported antibodies, including complementarity determining regions (CDRs) with different
characteristics. This report contributes to our knowledge of neutralizing antibodies that bind to …

… antibodies to the highly conserved fusion loop region of E domain II. Mutations at fusion loop
… The results show that hMAbs directed against the highly conserved E protein fusion loop …

… regions (V1-V5). The variable loop regions occlude the constant regions to escape from …
The CDR H3 loop of HIV broadly neutralizing antibody PG9 plays an essential role in stabilizing …

… neutralizing monoclonal antibody (mAb) SD6. The mAb SD6 binds to the long flexible GH‐loop
of … with a synthetic peptide corresponding to the GH‐loop of VP1, were fitted to the cryo‐…

… alterations in residues in one of two regions of gp120: loop D or the V5 region (73) (see Fig.
S1 in … amino acid sequence variation within the CD4 binding loop region (see Fig. S1 in the …

… -loop sequences in the strain specificity of antibody-mediated neutralization. To investigate
if certain variable loops might be responsible for the strain-specific neutralizing activity …