Effectiveness of remdesivir, lopinavir/ritonavir, and favipiravir for COVID-19 treatment: a systematic review

WF Qomara, DN Primanissa, SH Amalia… - … journal of general …, 2021 - Taylor & Francis
… This study provides an overview of the evidence-based role of remdesivir, favipiravir, and
lopinavir/ritonavir in the management of COVID-19. A thorough assessment of the benefit-risk …

A review of the preclinical and clinical efficacy of remdesivir, hydroxychloroquine, and lopinavir-ritonavir treatments against COVID-19

D Maciorowski, SZE Idrissi, Y Gupta… - … the Science of Drug …, 2020 - journals.sagepub.com
remdesivir, hydroxychloroquine, and lopinavir-ritonavir combinations. These compounds
have been frequently touted as top candidates to treat COVID-19, but recent clinical reports …

Comparable Efficacy of Lopinavir/Ritonavir and Remdesivir in Reducing Viral Load and Shedding Duration in Patients with COVID-19

CM Kim, JK Chung, S Tamanna, MS Bang, M Tariq… - Microorganisms, 2024 - mdpi.com
… This study compared the effects of lopinavir/ritonavir and remdesivir on COVID-19 patients
… three groups: lopinavir/ritonavir, remdesivir, and control. We assessed the efficacy of these …

Role of Lopinavir/Ritonavir in the treatment of Covid-19: a review of current evidence, guideline recommendations, and perspectives

S Meini, A Pagotto, B Longo, I Vendramin… - Journal of clinical …, 2020 - mdpi.com
… review the available evidence on the efficacy of LPV/r in COVID-… , a somewhat higher binding
efficiency, and a somewhat higher … that both remdesivir and LPV (but not ritonavir) inhibited …

Efficacy of lopinavir/ritonavir compared with standard care for treatment of coronavirus disease 2019 (COVID-19): a systematic review

TI Hariyanto, E Kristine, C Jillian Hardi… - … Current Drug Targets …, 2021 - ingentaconnect.com
… is administered, the effects of other pharmacologic therapies given concurrently, such as
steroids, as well as other experimental treatment options such as chloroquine and remdesivir. …

Comparative effectiveness of Lopinavir/Ritonavir‐based regimens in COVID‐19

J Qu, GH Li, JJ Wang, GF He, JJ Huang… - Clinical and …, 2021 - Wiley Online Library
… Here we evaluated the efficacy of the Lopinavir/Ritonavir (… We evaluated the medication
efficacy by comparing the time of … /r and Novaferon may have better efficacy against COVID-19. …

[PDF][PDF] Clinical efficacy of lopinavir/ritonavir in the treatment of Coronavirus disease 2019.

XT Ye, YL Luo, SC Xia, QF Sun, JG Ding… - European Review for …, 2020 - europeanreview.org
… The study aimed to investigate whether lopinavir/ritonavir (LPV/r) in combination with other
… Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and inter…

Adverse effects of remdesivir, hydroxychloroquine and lopinavir/ritonavir when used for COVID-19: systematic review and meta-analysis of randomised trials

A Izcovich, RA Siemieniuk, JJ Bartoszko, L Ge… - BMJ open, 2022 - bmjopen.bmj.com
… -19 include remdesivir, hydroxychloroquine with or without azithromycin, and lopinavir/ritonavir.
None of these drugs have high certainty evidence evaluating their effectiveness for key …

Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV

TP Sheahan, AC Sims, SR Leist, A Schäfer… - Nature …, 2020 - nature.com
… a combination of lopinavir, ritonavir and interferon beta (LPV/RTV-IFNb) is currently
being evaluated in humans in the Kingdom of Saudi Arabia. Here, we show that remdesivir (RDV) …

[HTML][HTML] Insights into antiviral mechanisms of remdesivir, lopinavir/ritonavir and chloroquine/hydroxychloroquine affecting the new SARS-CoV-2

K Uzunova, E Filipova, V Pavlova, T Vekov - Biomedicine & …, 2020 - Elsevier
… An in silico test of the COVID-19 RdRp built model suggested the effectiveness of remdesivir
as a potent drug [22]. SARS-CoV and SARS-CoV-2 both belong to the betacoronaviruses of …