… , with GMTs between 1:19.5 (59% seroconversion) and 1:18.3 (47% seroconversion) for
the high and the low doses, respectively. T cell responses were below the limit of detection in …

… single immunization with relatively low dose of Ad26.COV2.S effectively protected against
SARS-CoV-2 challenge … We observed that low doses of Ad26.COV2.S protected against Ad26.…

… of pseudotyped SARS-CoV-2 … by SARS-CoV-2 infection by using peripheral blood mononuclear
cells (PBMCs) from Donor 3 in two independent sorting strategies to isolate SARS-CoV-2…

Importance There is no specific antiviral therapy recommended for coronavirus disease 2019
(COVID-19). In vitro studies indicate that the antiviral effect of chloroquine diphosphate (CQ…

… Understanding the pathogenesis of the SARS-CoV-2 infection is key to developing …
SARS-CoV-2 intranasal infection in ferrets and hamsters with low doses of low-passage SARS-CoV-…

… using a lower infectious dose, we … SARS-CoV-2 transmission dynamics is important for
designing appropriate strategies for a more effective response to emerging variants of SARS-CoV…

… A low dose intranasal challenge of the same SARS-CoV-2 virus (5 × 10 2 pfu) appeared to
result in infection of only one ferret which shed detectable viral RNA in the upper respiratory …

Background The effectiveness and sustainability of current public health interventions designed
to prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission …

… coronavirus 2 (SARS-CoV-2) … SARS-CoV-2 genomic diversity, the National Institute of
Allergy and Infectious Diseases within the National Institutes of Health established the SARS-CoV-…

… two vaccine doses and then inoculated with SARS-CoV-2. Those that received the lowest
dose showed signs of controlling the infection, and those receiving the highest dose appeared …