… inflammatory markers, whereas these were decreased in the absence, or with the clearance,
of infection. We conclude that airway inflammation follows … are eradicated from the airways. …

… the effects of airway inflammation and its relationship to progressive lung disease in CF …
the inflammatory response in the airway of the CF patient, the clinical measures of inflammation, …

… did not differentiate those with and without lower airway infection; however, … lower airway
inflammation as well as mediators linked to airway remodeling play an active role in pulmonary …

… CF animal models mimicking human lung disease may provide an important insight into
the pathogenesis of lung inflammation in CF and identify new therapeutic targets. …

… Airway inflammation is now recognized as a major factor in the pathogenesis of lung disease
in cystic fibrosis … influx into the airways of neutrophils, which damage the lung by releasing …

… Airway inflammation may persist for a variable period following clearance … reduced lung
function. No relation was apparent however, between markers of airway inflammation and lung …

… inflammatory lung diseases such as asthma and non-CF bronchiectasis, suggesting common
(not CF-specific) pathophysiological changes probably related to airway inflammation and/…

… There is also evidence to suggest that airway inflammation may be excessive and
sustained relative to the infectious stimuli. Studies have shown dysregulation of both pro-…

… We hypothesized that infection initiates and then maintains lower airway inflammation in
CF patients. Cytokines have multiple functions. TNF-a and IL-1b are associated with the initial …

… Inflammation in the CF airways occurs from a young … in airway inflammation in CF, the
contribution of the intrinsic genetic defect to the CF inflammatory phenotype, and anti-inflammatory …