… understandings of lung physiology, where local infections progress … SARS-CoV-2 infection into four phases: (1) Upper and lower respiratory tract infection, (2) COVID-19 associated lung …
… Increased PAI1 expression was also observed in mice infected with SARS-CoV 113 . Interestingly, in this mouse model, PAI1 protected mice from extensive lung haemorrhage, which …
… in vivo infection with SARS-CoV-2 in human lung … lung tissues of LoM infected with SARS-CoV or SARS-CoV-2 (Extended Data Fig. 2a). Consistent with previous results 17 , MERS-CoV …
… of lungs with severe SARS-CoV-2 infection in our series confirms the presence of DAD in different evolution phases associated with variable co-morbidities and super-infections. …
… basis of lung injury remains incompletely understood. Here, we analyze pulmonary immune responses and lung … In conclusion, we demonstrate that SARS-CoV-2 triggers profibrotic …
… Our organoids also enable facile exploration of SARS-CoV-2 distal lunginfection, … infection could compromise protective lung glycosaminoglycans and precipitate a vicious infection …
L He, Y Ding, Q Zhang, X Che, Y He… - The Journal of …, 2006 - Wiley Online Library
… The authors have previously shown that acute lung injury (ALI) produces a wide spectrum of … (SARS) and that the SARScoronavirus (SARS-CoV) nucleoprotein is detectable in the lungs…
… lung epithelial infection models to understand initial responses of proximal and distal lung epithelium to SARS-CoV-2 infection… of distal lung AT2 cells are readily infected by SARS-CoV-…
… SARS-CoV-2 and SARS-CoVinfection of the human lungs, we treated ex vivo human lung tissues with NA, followed by SARS-CoV-2 or SARS-CoV challenge. Our results showed that …