Lung infections and aging

KC Meyer - Ageing research reviews, 2004 - Elsevier
… The presence of diseases that alter lung structure such as COPD or bronchiectasis also
increase the likelihood of gram-negative rods as a cause of bacterial pneumonia. Viral …

Neutrophils ameliorate lung injury and the development of severe disease during influenza infection

MD Tate, YM Deng, JE Jones, GP Anderson… - The Journal of …, 2009 - journals.aai.org
infection in humans. Therefore, it was important to ascertain bacterial counts in the lungs
of virus-infected mice to ensure that severe disease … Seven days after virus infection, BAL …

Chronic lung disease of prematurity. The role of intra-uterine infection

A Lyon - European journal of pediatrics, 2000 - Springer
… [41] reported that in infants of birth weight less than 2000 g, chorioamnionitis was associated
with less acute lung disease but a higher incidence of chronic lung disease, defined in this …

New opportunities for managing acute and chronic lung infections

WOCM Cookson, MJ Cox, MF Moffatt - Nature Reviews Microbiology, 2018 - nature.com
… , acute lung infection in the presence of underlying chronic obstructive pulmonary disease
(COPD… , which means that lung infections are the largest cause of disease burden to humanity. …

Respiratory infection and the impact of pulmonary immunity on lung health and disease

JP Mizgerd - American journal of respiratory and critical care …, 2012 - atsjournals.org
… Impressive as they are, these figures underestimate the full impact of such infections, … disease
[COPD], or asthma) tend to be attributed to the underlying disease rather than lung infection

The systemic response to lung infection

JC Deng, TJ Standiford - Clinics in chest medicine, 2005 - chestmed.theclinics.com
… , chemokines, IL-12, and IFN-γ in lung tissue with little to no measurable induction in plasma.
… to be localized to the infected lung, with minimal expression in the contralateral lung and no …

Defining the risk and associated morbidity and mortality of severe respiratory syncytial virus infection among infants with chronic lung disease

B Paes, B Fauroux, J Figueras-Aloy, L Bont… - Infectious diseases and …, 2016 - Springer
Severe RSV infection in infants and young children with CLD/BPD poses a significant … of
RSV infection in this well-recognized population at high risk for severe disease are needed to …

Early infection and progression of cystic fibrosis lung disease

C Koch - Pediatric pulmonology, 2002 - Wiley Online Library
… The products of exocrine glands become inspissated, resulting in a multisystem disease
of progressive lung infection and inflammation ultimately lead to respiratory failure.CF lungs

Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease

EY Kim, JT Battaile, AC Patel, Y You, E Agapov… - Nature medicine, 2008 - nature.com
… To investigate the possible link between acute viral infection and chronic inflammation, we
developed a mouse model of chronic inflammatory lung disease. The infectious agent used in …

Lung disease in primary antibody deficiency

N Verma, B Grimbacher, JR Hurst - The Lancet Respiratory Medicine, 2015 - thelancet.com
… Respiratory infection is a common presenting feature of PAD and lung complications of …
PAD in children, upper airway (sino-nasal) manifestations of adult PAD, or lung disease in …