Extracellular vesicles in the pathogenesis and treatment of acute lung injury

Q Hu, S Zhang, Y Yang, JQ Yao, WF Tang… - Military Medical …, 2022 - Springer
… leads to lung inflammation and injury. Recently, studies on the role of extracellular vesicles
(EVs) in … cell activities, including inflammation and injury responses, have attracted attention. …

[HTML][HTML] Emerging role of extracellular vesicles in lung injury and inflammation

Z Lanyu, H Feilong - biomedicine & pharmacotherapy, 2019 - Elsevier
… and diagnoses for lung injury and inflammation in this review. … the extracellular vesicles of
100 nm-1 μm in diameter, but not the term “microparticle (MP)”. Exos refer to smaller vesicles (…

Mesenchymal stem cell derived secretome and extracellular vesicles for acute lung injury and other inflammatory lung diseases

A Monsel, Y Zhu, V Gudapati, H Lim… - Expert opinion on …, 2016 - Taylor & Francis
… /or MSC extracellular vesicles as treatment for acute lung injury and other inflammatory
lung … application of MSC extracellular vesicles remains promising, primarily due to ability of …

Extracellular vesicles in lung disease

H Kubo - Chest, 2018 - Elsevier
Accumulating evidence suggests that extracellular vesicles (EVs) play a role in the pathogenesis
of lung diseases. These vesicles include exosomes, ectosomes (ie, microparticles, …

The role of extracellular vesicles in traumatic brain injury-induced acute lung injury

CN Zhang, FJ Li, ZL Zhao… - … of Physiology-Lung …, 2021 - journals.physiology.org
… unstable zinc and inflammatory mediators in the lungs, including tumor necrosis factor (TNF…
of lung injury. Changes in respiratory dynamics after TBI can also lead to lung damage due …

[HTML][HTML] Extracellular vesicles in lung health, disease, and therapy

MJ McVey, M Maishan, KEC Blokland… - … of Physiology-Lung …, 2019 - journals.physiology.org
… introducing extracellular vesicles and their emerging roles in lung physiology … lung injury
(63, 113), and in patients with ARDS and are in turn capable of inducing significant lung injury

Systematic review of extracellular vesicle‐based treatments for lung injury: are EVs a potential therapy for COVID‐19?

K Khalaj, RL Figueira, L Antounians… - … extracellular vesicles, 2020 - Wiley Online Library
… This review indicates that EV‐based therapies hold great potential for COVID‐19 related
lung injuries as they target multiple pathways and enhance tissue regeneration. However, …

Therapeutic use of extracellular vesicles for acute and chronic lung disease

EN Worthington, JS Hagood - International journal of molecular sciences, 2020 - mdpi.com
… This review will describe current published research using EVs as a potential therapy for
acute lung injury/acute respiratory distress syndrome (ALI/ARDS), bronchopulmonary dysplasia …

Extracellular vesicles: novel communicators in lung diseases

A Mohan, S Agarwal, M Clauss, NS Britt… - Respiratory research, 2020 - Springer
… The lung is the organ with the highest vascular density in the human body. It is therefore …
endothelium of the lung contributes significantly to the circulation of extracellular vesicles (EVs), …

Mesenchymal stromal cells modulate macrophages in clinically relevant lung injury models by extracellular vesicle mitochondrial transfer

TJ Morrison, MV Jackson, EK Cunningham… - American journal of …, 2017 - atsjournals.org
… MSC-derived extracellular vesicles (EVs) have been shown to recapitulate many of the
beneficial effects of MSCs in lung injury in vivo. These MSC-derived EVs have also been shown …