… Thirty minutes before model construction, rats in PDTC group were subjected to intravenous
injection of NFκB specific inhibitor PDTC (Sigma-Aldrich, St. Louis, MO, USA) at a dose of …

… lung injury. In this study, the anti-inflammatory effects of apigenin on lipopolysaccharide (LPS)-induced
acute lung injury (… significantly induced a decrease in lung wet weight/dry weight …

… targeting NF-κB in the endothelium provides an attractive approach to mitigate PMN-mediated
vascular injury… This review discusses the role and regulation of NF-κB in the context of EC …

… NF-κB, and activation of p38MAPK signaling may be one of the mechanisms of acute lung
injury. … signaling may be involved in the activation of NF-κB in LPS-induced acute lung injury. …

… translocation of NF-κB decreases the expression of NF-κB-… severity of endotoxemia-induced
acute lung injury [59]. In the … IκB and NF-κB p65 subunit nuclear translocation in lung tissue …

… of crocetin on acute lung injury induced by … lung injury induced by LPS were investigated
systematically. The involvement of NF-ΚB pathway in the development of acute lung injury was …

… in lung injury at 48 h. To determine whether intervention in the NF-κB pathway could prevent
progression to lung injury … -345541) to down-regulate NF-κB activation following the onset of …

… in our understanding of the role of NF-κB and interactions between NF-κB and other
transcription factors in the pathogenesis of acute lung injury. MOLECULAR BIOLOGY OF NF-κB …

… Changes in the lung tissues We firstly explored lung injury in each group. Compared to the
NS group (Fig. 2 A), the lung of the LPS group exhibited a more severely distorted structure (…

… p53 negatively regulates NF-κB activity by decreasing binding of NF-κB to the promoters of
… −/− inflammatory cells to LPS stimulation and enhancing lung injury in LPS-treated p53 −/− …