… the role of the NLRP3 inflammasome during ALI and the contribution of extracellular
histones to NLRP3 inflammasome activation. The NLRP3 inflammasome and caspase-1 were …

… acute lung injuries, such as transfusion-related acute lung injury, ventilator-induced lung
injury, … This article summarizes recent research on the inflammasome and reviews proposed …

… is important in ventilator-induced lung injury (VILI) but the exact … of the intracellular danger
sensor NLRP3 inflammasome. … preexisting lung injury and may even induce lung injury in …

… induce acute lung injury 31. To determine whether melatonin could inhibit activation of the
NLRP3 inflammasome, we detected the level of caspase-1 and IL-1β in the lung homogenate …

… and discuss the contribution of the NLRP3 inflammasome to the pathology of lung diseases.
… The NLRP3 inflammasome has also been implicated in a model of lung injury induced by …

… or cause lung injury, known as ventilator-induced lung injury (VILI). However, the mechanisms
are unclear. The NLR family pyrin domain containing 3 (NLRP3) inflammasome is a vital …

… NLRP3 inflammasome activation is specifically required for the development of hypoxemia,
but not for neutrophil infiltration or alveolar leakage in our LPS-plus-MV lung injury model. …

… affecting the activity of NLRP3 inflammasome in LPS-induced acute lung injury in mice.
Although NLRP3 inflammasome activation is critical for driving acute lung inflammation aiding in …

… This study showed that RIP3 participates in the NLRP3 inflammasome activation in LPS-induced
lung injury. This pathway is independent of RIP3 associated necroptosis. GSK872, a …

… SB203580 significantly suppressed the acute lung injury and excessive lung inflammation
in vivo, consistent with the reduced expression of the NLRP3 inflammasome and IL‑1β and …