… The lung is the major target organ of SARS-CoV-2 infection, … lung epithelial and endothelial
injury induced by SARS-CoV-2… , and immune cell-mediated lung injury. Finally, we discuss …

… COVID-19 associated lung injury (CALI; Box 1), (3) SIRS, and (4) systemic failure (Figure 1).
… COVID-19 Associated Lung Injury (CALI). SARS-CoV-2 appears to induce acute lung injury …

The worldwide pandemic caused by the SARS-CoV-2 virus has resulted in over 84,407,000
cases, with over 1,800,000 deaths when this paper was submitted, with comorbidities such …

… The authors have previously shown that acute lung injury (ALI) produces a wide spectrum of
… (SARS) and that the SARS coronavirus (SARS-CoV) nucleoprotein is detectable in the lungs…

… disease and infection of the lung. The development of SARS-CoV-2 MA10 provides a much-…
spectrum and acute lung injury phenotype observed in human SARS-CoV-2 infections. It …

… In a follow-up experimental study, we compared animals with acute lung injury under controlled
MV and spontaneously breathing without MV. Lung injury was induced by lung lavage in …

… Severe lung injury in SARS-CoV–infected Chinese macaques has not been detected until 7
… To determine the effect of anti-S antibody on the extent of SARS-CoV–mediated lung injury, …

… crucial role in severe acute lung injury and that the SARS-CoV receptor ACE2 has a protective
role in acute lung failure 18 (Fig. 2a). Notably, experimental SARS-CoV infections of wild-…

… More clinical evidences indicate that SARS-CoV-2 infection can damage alveolar function
in severe patients. In order to create the human lung infection model by SARS-CoV-2 in vitro, …

… lung injury in animal models and human ARDS, here we systematically evaluate a model
of experimental acute lung injury as a result of SARS-CoV-2 … demonstrate acute SARS-CoV-2 …