Tetrahydroberberrubine attenuates lipopolysaccharide-induced acute lung injury by down-regulating MAPK, AKT, and NF-κB signaling pathways

X Yu, S Yu, L Chen, H Liu, J Zhang, H Ge… - Biomedicine & …, 2016 - Elsevier
… LPS-induced acute lung injury by inhibiting the release of inflammatory cytokines and
suppressing the activation of MAPKs, AKT, and NF-κB signaling pathways, which implicates it as a …

Echinacea polysaccharide alleviates LPS-induced lung injury via inhibiting inflammation, apoptosis and activation of the TLR4/NF-κB signal pathway

H Zhang, W Lang, S Wang, B Li, G Li, Q Shi - International …, 2020 - Elsevier
… might attenuate LPS-induced lung injury by suppressing inflammatory responses and …
signaling pathway. Therefore, we believe that EP has great potential in the treatment of lung injury. …

Anti-inflammatory effect of Yam Glycoprotein on lipopolysaccharide-induced acute lung injury via the NLRP3 and NF-κB/TLR4 signaling pathway

X Niu, L Zang, W Li, X Xiao, JJ Yu, Q Yao… - International …, 2020 - Elsevier
… Acute lung injury (ALI) is a common lung disease … effect of yam glycoprotein on lung tissue
changes. We examined … Immunohistochemical analyses of NLRP3 and p-p65 in lung tissue …

[HTML][HTML] Tangeretin attenuates lipopolysaccharide-induced acute lung injury through Notch signaling pathway via suppressing Th17 cell response in mice

M Li, Y Zhao, D Qi, J He, D Wang - Microbial Pathogenesis, 2020 - Elsevier
… that are involved in the development of acute lung injury (ALI). This study investigated the …
We further investigated the effect of tangeretin on Notch signaling pathway. Notch inhibition …

Hyaluronan ameliorates LPS-induced acute lung injury in mice via Toll-like receptor (TLR) 4-dependent signaling pathways

C Xu, G Chen, W Yang, Y Xu, Y Xu, X Huang… - International …, 2015 - Elsevier
pathway … p38 pathways, we further examined MAPK signaling pathways to pinpoint the
anti-inflammatory effect of HA. The expression levels of proteins related to these pathways were …

Protective effect of taurine on sepsis‑induced lung injury via inhibiting the p38/MAPK signaling pathway

J Chen, X Xue, J Cai, L Jia… - Molecular Medicine …, 2021 - spandidos-publications.com
… that taurine alleviated sepsis‑induced lung injury, which was associated with suppression of
… p38/MAPK signaling pathway. Therefore, the p38/MAPK signaling pathway may serve as a …

… Rh2 ameliorates lipopolysaccharide-induced acute lung injury by regulating the TLR4/PI3K/Akt/mTOR, Raf-1/MEK/ERK, and Keap1/Nrf2/HO-1 signaling pathways in …

YH Hsieh, JS Deng, YS Chang, GJ Huang - Nutrients, 2018 - mdpi.com
… Several signal transduction pathways have been suggested … Raf-1/MEK/ERK signaling
pathway is involved the inflammatory … for preventing acute lung injury and inhibiting inflammation. …

Corylin ameliorates LPS-induced acute lung injury via suppressing the MAPKs and IL-6/STAT3 signaling pathways

IC Chen, SC Wang, YT Chen, HH Tseng, PL Liu… - Pharmaceuticals, 2021 - mdpi.com
Acute lung injury (ALI) is a high mortality disease with acute inflammation. Corylin is a
compound isolated from the whole plant of Psoralea corylifolia L. and has been reported to have …

NLRC5 negatively regulates inflammatory responses in LPS-induced acute lung injury through NF-κB and p38 MAPK signal pathways

Y Wang, C Huang, E Bian, T Lei, X Lv, J Li - Toxicology and Applied …, 2020 - Elsevier
… of acute lung injury. In this study we successfully established a model of acute lung injury
expression was apparently elevated in mouse lung tissue and primary alveolar macrophages. …

… effects against lipopolysaccharide-induced acute lung injury by regulating the crosstalk between the CX3CL1-CX3CR1 axis and NF-κB pathway in CX3CL1-knockout …

XM Ding, L Pan, Y Wang, QZ Xu - … Journal of Molecular …, 2016 - spandidos-publications.com
signaling pathway involved in the development of lung injury. The results indicated that, on
the one hand, baicalin exerted potent anti-inflammatory effects by inhibiting the activation of …